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Displaying results 591 - 600 of 10000 in total
  1. Drug

    Aurothioglucose

    go.drugbank.com/drugs/DB09121
    ApprovedWithdrawn

    Many if not most gold compounds that were indicated for rheumatoid arthritis therapy have since been replaced with the use of various current disease modifying anti-rheumatic drugs (DMARDs) like methotrexate

  2. Drug

    Pravastatin

    go.drugbank.com/drugs/DB00175
    ApprovedInvestigational

    It was the first statin administered as the active form and not as a prodrug.[T274] This drug was developed by Sankyo Co. … Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved in 1991.

    Products: Nu-pravastatin Tablets
  3. Drug

    Bismuth subgallate

    go.drugbank.com/drugs/DB13909
    Approved

    Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter

  4. Drug

    Acetylsalicylic acid

    go.drugbank.com/drugs/DB00945
    ApprovedInvestigationalVet approved

    Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate

    Mixtures: Phenaphen No 3 Cap, Phenaphen No 4 CapCategories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-Narcotic
  5. Drug

    Rosuvastatin

    go.drugbank.com/drugs/DB01098
    ApprovedInvestigational

    [A181409,A1793] However, the results of the SATURN trial[A181427] concluded that despite this difference in potency, there was no difference in their effect on the progression of coronary atherosclerosis … elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver.

    Products: Nb-rosuvastatin
  6. Drug

    Liotrix

    go.drugbank.com/drugs/DB01583
    Approved

    Administration of levothyroxine alone is sufficient for maintaining serum T4 and T3 levels in most patients and combination hormone replacement therapy generally offers no therapeutic advantage. … It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight.

  7. Drug

    Bioallethrin

    go.drugbank.com/drugs/DB13746
    ApprovedWithdrawn

    A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin. … It is claimed to have low mammalian toxicity.

  8. Drug

    Pregabalin

    go.drugbank.com/drugs/DB00230
    ApprovedInvestigational

    [L1006,L7066] It may have dependence liability if misused but the risk appears to be highest in patients with current or past substance use disorders.[A31161] … [A187190] Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent

    Products: Nb-pregabalin, LYRICA 20MG/ML LOE Z EINN
  9. Drug

    Sunobinop

    go.drugbank.com/drugs/DB18955
    Investigational

    Sunobinop is under investigation in clinical trial NCT04035200 (Safety, Tolerability and Efficacy Study of V117957 in Subjects With Insomnia Associated With Alcohol Cessation).

    Synonyms: 2-quinoxalinecarboxylic acid, 4-((3-endo)-9-(3-exo)-bicyclo(3.3.1)non-3-yl-9-azabicyclo(3.3.1)non-3-yl)-3,4-dihydro-3-oxo-
  10. Drug

    Lopinavir

    go.drugbank.com/drugs/DB01601
    ApprovedInvestigational

    [saquinavir], [nelfinavir]), lopinavir is a peptidomimetic molecule - it contains a hydroxyethylene scaffold that mimics the peptide linkage typically targeted by the HIV-1 protease enzyme but which itself … [L11163] Lopinavir is marketed and administered exclusively in combination with [ritonavir] - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's