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Displaying results 6041 - 6050 of 10000 in total
  1. Drug

    Etofamide

    go.drugbank.com/drugs/DB13258
    Approved

    Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued [L5617].

  2. Drug

    TU-100

    go.drugbank.com/drugs/DB12467
    Investigational

    TU-100 has been used in trials studying the treatment of Abdominal Pain, Colonic Transit, Crohn's Disease, Rectal Sensation, and Gastric Emptying, among others.

  3. Drug

    N-Acetyl-glucosamine thiazoline

    go.drugbank.com/drugs/DB03747
    Experimental

    N-Acetyl-glucosamine thiazoline (NAG-thiazoline) is an analog of the oxazolinium bicyclic intermediate leading from N-acetylglucosamine to 1,6-anhydro-N-acetylmuramic acid.

  4. Drug

    Tetrahydrocannabivarin

    go.drugbank.com/drugs/DB11755
    Investigational

    Physiological effects of using cannabis make sense in the context of its receptor activity as the hippocampus and amygdala are primarily involved with regulation of memory, fear, and emotion. … Furthermore, THCV interacts with different transient receptor potential (TRP) channels including TRPV2, which may contribute to the analgesic, anti-inflammatory and anti-cancer effects of cannabinoids

    Categories: Serotonin Receptor Agonists, Serotonin 5-HT1 Receptor Agonists
  5. Drug

    SNS-314

    go.drugbank.com/drugs/DB06134
    Investigational

    Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis, leading to multiple rounds of endoreduplication and eventually cell death.

  6. Drug

    GT 389-255

    go.drugbank.com/drugs/DB05894
    Experimental

    It is expected to block fat absorption with fewer side effects than currently marketed lipase inhibitors. … Peptimmune’s lead product GT 389-255, is a novel lipase inhibitor and fat binding hydrogel polymer conjugate for the treatment of obesity which has completed single and multiple ascending dose (SAD and

  7. Drug

    Tanaproget

    go.drugbank.com/drugs/DB04787
    Experimental

    It is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective binding profile relative to most conventional progestins. … Because of this tanaproget may prove to produce fewer side effects in comparison. It is currently in the process of being developed for clinical use as a contraceptive by Ligand Pharmaceuticals.

  8. Drug

    Avena sativa flowering top

    go.drugbank.com/drugs/DB14253
    Approved

    Avena sativa flowering top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  9. Drug

    Imsidolimab

    go.drugbank.com/drugs/DB16658
    Investigational

    Imsidolimab is under investigation in clinical trial NCT03633396 (A Study to Evaluate the Efficacy and Safety of ANB019 in Subjects With Palmoplantar Pustulosis).

  10. Drug

    Methylprednisone

    go.drugbank.com/drugs/DB12952
    ApprovedInvestigationalWithdrawn

    Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.