Methylprednisone

DB12952ApprovedInvestigationalWithdrawnSmall molecule

Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.

Mechanism: Pharmacologically active on Glucocorticoid receptor
Curator reviewed
Formula / weight: C₂₂H₂₈O₅ · 372.461 g/mol (avg)
Also known as: 6-alpha-methylprednisone
Code names: NSC-63546

Resolves to

Compound

UNII621XR2W6OPCAS91523-05-6PubChem124653

Structure

InChIKeySVYCRJXQZUCUND-PQXSVQADSA-NSMILESC[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)CC(=O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12

Targets

P04150NR3C1

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

490Drug interactionsStructured to mechanism, not free text

22Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Methylprednisone, and which of those have an active Phase 3 trial?

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