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SynOV1.1
go.drugbank.com/drugs/DB17539InvestigationalIt is a recombinant oncolytic adenovirus, controlled by synthetic gene circuit, encoding the human immunostimulating factor cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF). … SynOV1.1 is an investigational cancer immunotherapy developed by SyngenTech.
Oxalic Acid
go.drugbank.com/drugs/DB03902ExperimentalA strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. … It is used as an analytical reagent and general reducing agent. [PubChem]
Categories: Compounds used in a research, industrial, or household settingBNT162a1 SARS-CoV-2 Vaccine
go.drugbank.com/drugs/DB15697Experimental[L15002, L15007] BNT162a1 is a uridine mRNA (uRNA) vaccine formulated in lipid nanoparticles for delivery via intramuscular injection. … BNT162a1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.
Synonyms: BNT162a1 SARS-CoV-2 VaccineBNT162c2 SARS-CoV-2 Vaccine
go.drugbank.com/drugs/DB15698ExperimentalBNT162c2 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech. … [L15002, L15007] BNT162c2 is a self-amplifying mRNA (saRNA) vaccine formulated in lipid nanoparticles for delivery via intramuscular injection.
Synonyms: BNT162c2 SARS-CoV-2 VaccineCol-118
go.drugbank.com/drugs/DB05778InvestigationalCol-118 is a unique formulation and presentation of Brimonidine, which is a selective alpha-2 adrenergic receptor agonist. … It is a believed to reduce erythema by constricting enlarged blood vessels in facial tissue.
CLX-0921
go.drugbank.com/drugs/DB05854ExperimentalCLX-0921 is investigated for use/treatment in diabetes mellitus type 2. CLX-0921 is a solid. CLX-0921 has a spectrum of activity that differs from commercially available thiazolidinediones. … It is a pharmacologically active antihyperglycemic agent that acts by increasing peripheral tissue sensitivity to insulin.
Categories: Heterocyclic Compounds, 1-RingLinifanib
go.drugbank.com/drugs/DB06080InvestigationalLinifanib (ABT-869) is a small molecule vascular endothelial growth factor (VEGF) receptor-based kinase inhibitor that is designed to suppress tumor growth by preventing the formation of new blood vessels … Linifanib is intended for the treatment of hematologic malignancies and the solid tumors.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 1-(4-(3-AMINO-1H-INDAZOL-4-YL)PHENYL)-3-(2-FLUORO-5-METHYLPHENYL)UREA, UREA, N-(4-(3-AMINO-1H-INDAZOL-4-YL)PHENYL)-N'-(2-FLUORO-5-METHYLPHENYL)-MCC
go.drugbank.com/drugs/DB05282InvestigationalThe product is a sterile biological composition in a sub-micron suspension. It is produced at the Bioniche manufacturing facility in Pointe-Claire, Quebec. … Mycobacterial Cell Wall-DNA Complex (MCC) is formulated from Mycobacterium phlei, a non-pathogenic strain of mycobacteria.
Orludodstat
go.drugbank.com/drugs/DB21498InvestigationalOrludodstat is a small molecule drug. The usage of the INN stem '-dodstat' in the name indicates that Orludodstat is a dihydro-orotate dehydrogenase (DHODH) inhibitor. … Orludodstat is under investigation in clinical trial NCT03404726 (A Study to Investigate BAY2402234, a Dihydroorotate Dehydrogenase (DHODH) Inhibitor, in Myeloid Malignancies).
Categories: Heterocyclic Compounds, 1-RingRamosetron
go.drugbank.com/drugs/DB09290InvestigationalRamosetron is a _serotonin 5-HT3 receptor antagonist_ commonly employed to treat nausea and vomiting, in addition to certain diarrheal conditions. … It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: NASEA(R) TABLET 0.1 MG, IRRIBOW TABLET 5 MCG