Search

Displaying results 6081 - 6090 of 10000 in total
  1. Drug

    Rosomidnar

    go.drugbank.com/drugs/DB17154
    Investigational

    Synonyms: (3'-5')d(c-a-c-g-c-a-c-g-c-g-c-a-t-c-c-c-c-g-c-c-c-g-t-g)
  2. Drug

    Metformin

    go.drugbank.com/drugs/DB00331
    ApprovedInvestigational

    It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.

    Mixtures: AMARYL®M 4 MG/ 1000 MG, AMARYL M 4 MG/1000 MG FİLM KAPLI TABLET, 30 ADETCategories: MATE 2 Substrates, MATE 1 Substrates
  3. Drug

    Guaifenesin

    go.drugbank.com/drugs/DB00874
    ApprovedInvestigationalVet approved

    After the negotiation between FDA and major manufacturers, a voluntary transition of labels for not using guaifenesin in children under the age of 4 years was endorsed by FDA in 2008 [F4525]. … to be safe and effective in children under the age of 6 years [F4525].

    Mixtures: RINOGEST EKSPEKTORAN 30 MG / 5 ML + 100 MG / 5 ML ŞURUP, 150 ML, N-ACETILCISTEÍNA 2 G + GUAYACOLATO DE GLICERILO 2 G JARABEInternational brands: Duratuss G
  4. Drug

    Prednisolone

    go.drugbank.com/drugs/DB00860
    ApprovedInvestigationalVet approved

    Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. … [A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]

    Synonyms: delta(1)-Hydrocortisone, delta(1)-DehydrocortisolInternational brands: Decortin H, Di-Adreson F
  5. Drug

    Raltitrexed

    go.drugbank.com/drugs/DB00293
    ApprovedInvestigational

    Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.

    Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingProducts: TOMUDEX ® 2 MG, TOMUDEX 2 MG FLAKON, 1 ADET
  6. Drug

    Simethicone

    go.drugbank.com/drugs/DB09512
    ApprovedInvestigational

    Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. … [A228308] It has a favourable safety profile as it is not systemically absorbed.[A228308] Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952.[A228308]

    Mixtures: NOAX 3, BROMUX D® 100/300 MG CÁPSULA.Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Terlipressin

    go.drugbank.com/drugs/DB02638
    ApprovedInvestigational

    Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin. … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor.

    Products: HAEMOPRESSIN® 1 MG, GLYPRESSIN ® 1 MG
  8. Drug

    Evalstotug

    go.drugbank.com/drugs/DB19410
    Investigational

    Evalstotug is under investigation in clinical trial NCT05271604 (A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck).

    Synonyms: Immunoglobulin G1-kappa, anti-[Homo sapiens CTLA4 (cytotoxic T-lymphocyte associated protein 4, CTLA-4, CD152)], monoclonal antibody, Immunoglobulin G1 [de-448-lysine], anti-(human cytotoxic T-lymphocyte-associated protein 4) (human monoclonal BA3071 γ1-chain), disulfide with human monoclonal BA3071 κ-chain, dimer
  9. Drug

    Treprostinil

    go.drugbank.com/drugs/DB00374
    ApprovedInvestigational

    However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room temperature. … [L41855,L41860] The first agent approved for the treatment of PAH was [epoprostenol], a synthetic prostacyclin that significantly increases patients' quality of life.

    Categories: Prostaglandins I, Cytochrome P-450 SubstratesProducts: REMODULIN ® INYECCIÓN 1 MG/ML, TREPOKS 50 MG/20 ML İNFÜZYONLUK ÇÖZELTİ , 1 ADET
  10. Drug

    Bromazepam

    go.drugbank.com/drugs/DB01558
    ApprovedIllicit

    It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: LEXOTAN TABLET 3 mg, Lexotanil 3 mg - Tabletten