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Cetuximab
go.drugbank.com/drugs/DB00002ApprovedInvestigational[A228083] EGFR has been implicated in various types of cancer, as it is often overexpressed in malignant cells [A227973] and EGFR overexpression has been linked to more advanced disease and poor prognosis … [A227963] EGFR is often mutated in certain types of cancer and serves as a driver of tumorigenesis.
Products: ERBITUX 100 MG/20 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET, ERBITUX 500 MG/100 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADETTestosterone
go.drugbank.com/drugs/DB00624ApprovedInvestigational[A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also synthesized in 1935.[A186943]
International brands: Andronate 100, Testamone 100Products: Testavan 20 mg/g Transdermales Gel, SUSTANON 250 MG AMPUL, 1 ADETTamsulosin
go.drugbank.com/drugs/DB00706ApprovedInvestigational[A178351] Tamsulosin was first approved by the FDA on April 15, 1997.[L6238] … Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.
Mixtures: DUODART 0,5 MG/0,4 MG KAPSÜL,30 KAPSÜL, DUODART 0,5 MG/0,4 MG KAPSÜL,90 KAPSÜLCategories: Peripheral alpha-1 blockers, Adrenergic alpha-1 Receptor AntagonistsAtezolizumab
go.drugbank.com/drugs/DB11595ApprovedInvestigational[L7489] Atezolizumab was granted FDA approval on 18 October 2016. … Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers.
Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: TECENTRIQ CONCENTRATE FOR SOLUTION FOR INFUSION 1200 MG/ 20 ML, TECENTRIQ 1200 MG / 20 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETFluocortolone
go.drugbank.com/drugs/DB08971ApprovedWithdrawnFluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders.
Mixtures: ULTRALAN POMAT, 10 GR, ULTRALAN POMAT, 20 GRProducts: ULTRALAN 20 MG TABLET, 10 ADET, ULTRALAN ORAL 5 MG TABLET, 10 ADETIodide I-131
go.drugbank.com/drugs/DB09293ApprovedInvestigationalAs a result of beta decay, approximately 10% of its energy and radiation dose is via gamma radiation, while the other 90% (beta radiation) causes tissue damage without contributing to any ability to see … Low levels of beta radiation are also known for causing cancer as this dose is highly mutagenic.
Products: MON.IYOT-131 0.37-7400 MBQ (10µ Cİ-200 M Cİ) ORAL KAPSÜL, 10 MCİ, MON.IYOT-131 0.37-7400 MBQ (10µ Cİ-200 M Cİ) ORAL KAPSÜL, 20 MCİEdoxaban
go.drugbank.com/drugs/DB09075ApprovedInvestigationalreduce the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) following 5-10 … This has prompted enthusiasm for newer agents such as dabigatran, apixaban, and rivaroxaban for effective clot prevention.
Categories: Heterocyclic Compounds, 1-RingProducts: LIXIANA 15 MG FILM KAPLI TABLET ,10 TABLET, LIXIANA 30 MGBuspirone
go.drugbank.com/drugs/DB00490ApprovedInvestigationalBelonging to the azaspirodecanedione drug class,[A180991] buspirone is a serotonin 5-HT<sub>1A</sub> receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates … Buspirone was first approved in 1986 by the FDA [A181751] and has been used to treat anxiety disorders, such as generalized anxiety disorder (GAD), and relieve symptoms of anxiety.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dioneFluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalHMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. … Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase.
Categories: Heterocyclic Compounds, 2-RingProducts: Fluvastatin Sandoz 20 mg - Hartkapseln, LESCOL XL 80 MG TABLET, 28 ADETEbastine
go.drugbank.com/drugs/DB11742ApprovedInvestigationalWithdrawnEbastine has been investigated for the treatment of Urticaria.
Categories: Heterocyclic Compounds, 1-RingProducts: EBAFIT 20 MG FILM KAPLI TABLET, 10 ADET, EBAFIT 10 MG FILM KAPLI TABLET, 20 ADET