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Selenocysteine
go.drugbank.com/drugs/DB02345InvestigationalIt is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for this amino acid. [PubChem]
Izumerogant
go.drugbank.com/drugs/DB21604ExperimentalThe usage of the INN stem '-rogant' in the name indicates that Izumerogant is a retinoic acid receptor-related orphan receptor gamma (RORY) antagonist and inverse agonist.
AZD 3355
go.drugbank.com/drugs/DB05404InvestigationalAZD 3355 is a reflux inhibitor used for the treatment of Gastroesophageal Reflux Disease. It is developed by AstraZeneca and is currently in phase I/II trials.
Endostar
go.drugbank.com/drugs/DB11727InvestigationalEndostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Phytic acid
go.drugbank.com/drugs/DB14981InvestigationalPhytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).
Monalizumab
go.drugbank.com/drugs/DB12824InvestigationalMonalizumab has been used in trials studying the treatment of Gynecologic Cancer, Chronic Lymphocytic Leukemia, and Squamous Cell Carcinoma of the Oral Cavity.
GTI-2501
go.drugbank.com/drugs/DB05406ExperimentalThe drug is in a phase II clinical trial in combination with docetaxel for the treatment of hormone refractory prostate cancer.
Ponazuril
go.drugbank.com/drugs/DB11452ExperimentalVet approvedPonazuril, sold by the Bayer Corporation under the trade name Marquis, is a drug currently approved for the treatment of equine protozoal myeloencephalitis in horses, caused by Sarcocystis neurona.
Edotecarin
go.drugbank.com/drugs/DB04882InvestigationalIt is member of the class of compounds called indolocarbazoles.
NCX 1015
go.drugbank.com/drugs/DB05825ExperimentalNCX 1015 is nitric oxide-releasing derivative of prednisolone developed for the treatment of inflammatory bowel disease (IBD) by NicOx SA.