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Displaying results 6111 - 6120 of 8696 in total
  1. Drug

    XL281

    go.drugbank.com/drugs/DB05190
    Investigational

    XL281 is a novel anticancer compound designed to potently inhibit the RAS/RAF/MEK/ERK signaling pathway. Mutational activation of RAS occurs in about 30 percent of all human tumors, including non-small cell lung, pancreatic, and colon ca...

  2. Drug

    Talinolol

    go.drugbank.com/drugs/DB11770
    Investigational

    Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  3. Drug

    APG-157

    go.drugbank.com/drugs/DB18683
    InvestigationalNutraceutical

    APG-157 consists of zinflavonoids being investigated for the treatment of cancers.

  4. Drug

    Roniciclib

    go.drugbank.com/drugs/DB12974
    Investigational

    Roniciclib has been investigated for the treatment of Small Cell Lung Carcinoma.

  5. Drug

    Talarozole

    go.drugbank.com/drugs/DB13083
    Investigational

    Talarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation.

    Categories: Cytochrome P-450 Enzyme Inhibitors
  6. Drug

    Teneligliptin

    go.drugbank.com/drugs/DB11950
    Investigational

    Teneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus.

  7. Drug

    GSK-2018682

    go.drugbank.com/drugs/DB11987
    Investigational

    GSK2018682 has been investigated for the treatment of Multiple Sclerosis, Relapsing-Remitting.

  8. Drug

    RTX-117

    go.drugbank.com/drugs/DB28443
    Experimental

    RTX-117 is being investigated for Charcot-Marie-Tooth disease (CMT).[L54166]

  9. Drug

    Amobarbital

    go.drugbank.com/drugs/DB01351
    ApprovedIllicit

    A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmac...

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
  10. Drug

    Felzartamab

    go.drugbank.com/drugs/DB16375
    Investigational

    Felzartamab is under investigation in clinical trial NCT04145440 (Trial to Assess Safety and Efficacy of MOR202 in Anti-pla2r + Membranous Nephropathy (Amn)).