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Vafidemstat
go.drugbank.com/drugs/DB16446InvestigationalVafidemstat is under investigation in clinical trial NCT03867253 (Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease).
SC-236
go.drugbank.com/drugs/DB14059ExperimentalSC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) [L2964] that has been studied in cancer therapy [A33375], lower back pain [A33376], and inflammation [A33373], [A33374
Budigalimab
go.drugbank.com/drugs/DB16668InvestigationalWith IV Modified FOLFIRINOX (Mffx) With or Without IV Budigalimab Compared to Mffx in Adult Participants With Untreated Pancreatic Cancer Metastasis). … Budigalimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination
CMC 001
go.drugbank.com/drugs/DB05353InvestigationalCMC 001 is an orally administered MRI contrast agent in development for enhancement of the liver, bile ducts and gastrointestinal tract.
MLN2222
go.drugbank.com/drugs/DB06503ExperimentalMLN2222 is a novel, proprietary recombinant protein that blocks both the C3 and C5 convertases, which are essential components of the complement activation pathway.
AV-COVID-19
go.drugbank.com/drugs/DB15802InvestigationalAV-COVID-19 is a vaccine composed of autologous dendritic cells loaded with SARS-CoV-2 antigens and with or without Granulocyte-macrophage colony-stimulating factor (GM-CSF). … As of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine.
Acadesine
go.drugbank.com/drugs/DB04944InvestigationalAcadesine (AICA-riboside) is a purine nucleoside analog with anti-ischemic properties that is currently being studied (Phase 3) for the prevention of adverse cardiovascular outcomes in patients undergoing
Rilapladib
go.drugbank.com/drugs/DB05119InvestigationalLp-PLA2 is an enzyme associated with the formation of atherosclerotic plaques.
Kinetin
go.drugbank.com/drugs/DB11336ApprovedIt was shown to naturally exist in DNA of organisms including humans and various plants.
GTI 2040
go.drugbank.com/drugs/DB05801InvestigationalIt belongs to the family of drugs called antisense oligonucleotides.