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Luspatercept
go.drugbank.com/drugs/DB12281ApprovedInvestigationalLuspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1.
Verubecestat
go.drugbank.com/drugs/DB12285InvestigationalIn the study, administration of Verubecestat at doses of 12, 40 and 60 mg resulted in a dose-dependent and sustained reduction in the levels of Ab40, a measure of BACE1 activity, in CSF from baseline of
Simendan
go.drugbank.com/drugs/DB12286ExperimentalCategories: Compounds used in a research, industrial, or household settingForetinib
go.drugbank.com/drugs/DB12307InvestigationalForetinib has been used in trials studying the treatment of Cancer, Breast Cancer, Carcinoma, Renal Cell, Recurrent Breast Cancer, and Neoplasms, Head and Neck, among others. Foretinib is an orally available small molecule compound desig...
Sagopilone
go.drugbank.com/drugs/DB12391InvestigationalIt is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to combat several forms of cancer. … Epothilones are 16-member ring macrolides with antimicrotubule activity that share a similar mechanism of action to the taxanes but have demonstrated potent antiproliferative activity in several different
Sulforaphane
go.drugbank.com/drugs/DB12422InvestigationalIt is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.
Categories: Compounds used in a research, industrial, or household settingTempol
go.drugbank.com/drugs/DB12449InvestigationalTempol has been used in trials studying the treatment of Anal Cancer.
Categories: Compounds used in a research, industrial, or household settingPyrazoloacridine
go.drugbank.com/drugs/DB12549InvestigationalPyrazoloacridine has been used in trials studying the treatment of Lung Cancer, Liver Cancer, Breast Cancer, Melanoma (Skin), and Metastatic Cancer, among others.
Categories: Compounds used in a research, industrial, or household settingAbexinostat
go.drugbank.com/drugs/DB12565InvestigationalIt is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity.
Mosedipimod
go.drugbank.com/drugs/DB12592InvestigationalMosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced Neutropenia.