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Gadoxetic acid
go.drugbank.com/drugs/DB08884ApprovedInvestigationalGadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. … [A263146] Gadoxetic acid, under the form gadoxetate disodium, is marketed by Bayer HealthCare Pharmaceuticals under the brand name EOVIST and FDA approved in 2008.[A263151]
Categories: Compounds used in a research, industrial, or household settingProducts: Primovist 0.25 mmol/ml Solution for injection, PRIMOVIST 0.25 MMOL/ML, SOLUTION FOR INJECTIONExenatide
go.drugbank.com/drugs/DB01276ApprovedInvestigationalIt activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control[L42690].
Products: BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection, BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MGBusulfan
go.drugbank.com/drugs/DB01008ApprovedInvestigationalIt has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. … According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Products: Busulfan Kabi Injection 6mg/ml Concentrate for Solution for Infusion, Busulfan for InjectionGallium nitrate
go.drugbank.com/drugs/DB05260ApprovedInvestigational[A17097] GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US for reasons other than safety or effectiveness. … Gallium nitrate is a nitrate salt of [DB14524], a heavy metal that has been used as a diagnostic agent.[A260816] Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone.
Synonyms: Nitric acid, gallium salt, anhydratePertuzumab
go.drugbank.com/drugs/DB06366ApprovedInvestigationalIt was first approved by the FDA in 2012 for use with [docetaxel] and another HER2-targeted monoclonal antibody, [trastuzumab], in the treatment of metastatic HER2-positive breast cancer. … Its indicated conditions have since expanded to include use as both a neoadjuvant therapy and an adjuvant therapy in the treatment of HER2-positive breast cancers at high risk of recurrence.
Products: Perjeta 420 mg concentrate for solution for infusion, PERJETA CONCENTRATE FOR SOLUTION FOR INFUSION 420MG/14MLOlodaterol
go.drugbank.com/drugs/DB09080ApprovedInvestigationalSingle doses of olodaterol have been shown to improve forced expiratory volume in 1 sec (FEV1) for 24 h in patients with COPD, allowing once daily dosing. … Elevation of these two molecules induces bronchodilation by relaxation of airway smooth muscles.
Categories: Agents to Treat Airway Disease, Drugs for Obstructive Airway DiseasesProducts: Striverdi Respimat Solution for Inhalation 2.5 microgram/ actuation, SPIOLTO® RESPIMAT® RE-USABLE SOLUTION FOR INHALATION 2.5 MICROGRAM / 2.5 MICROGRAMalpha-Tocopherol acetate
go.drugbank.com/drugs/DB14003ApprovedAlpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. … At the moment however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use.
Mixtures: Gifteast Baja Salt Toothpaste Origin, TAMIPOOL FOR INJECTIONCategories: Compounds used in a research, industrial, or household settingHepatitis B Vaccine (Recombinant)
go.drugbank.com/drugs/DB11627ApprovedInvestigationalWithdrawnThere is no specific treatment for hepatitis. … Infection may also occur by the exposure of mucous surfaces, or intact or damaged skin to other body fluids such as saliva, mucosal secretions and semen.
Mixtures: Hexaxim Suspension for InjectionCategories: Antiinfectives for Systemic UseAmbrosia confertiflora pollen
go.drugbank.com/drugs/DB10872ApprovedAmbrosia confertiflora pollen is the pollen of the Ambrosia confertiflora plant. Ambrosia confertiflora pollen is mainly used in allergenic testing.
Synonyms: weakleaf bur ragweed pollen extractAgalsidase alfa
go.drugbank.com/drugs/DB15874ApprovedInvestigationalAgalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. … While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.
Products: REPLAGAL CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/ML