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Displaying results 611 - 620 of 10000 in total
  1. Drug

    Tamsulosin

    go.drugbank.com/drugs/DB00706
    ApprovedInvestigational

    [A178351] Tamsulosin was first approved by the FDA on April 15, 1997.[L6238] … Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.

    Mixtures: Duodart 0,5 mg/0,4 mg Hartkapseln, DuTamsul 0,5 mg/0,4 mg HartkapselnCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    Quinapril

    go.drugbank.com/drugs/DB00881
    ApprovedInvestigational

    [L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999.[L8423] … [L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.

    Mixtures: ACCUZIDE 20 MG/12.5 MG FILM TABLET, 30 ADET, ACCUZIDE FORT 20 MG/25 MG FILM KAPLI TABLET, 30 ADETProducts: ACCUPRIL (TABLETS 10 MG ), QUINAPRIL 10 MG TABLETAS
  3. Drug

    Nitisinone

    go.drugbank.com/drugs/DB00348
    Approved

    Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1 and Alkaptonuria.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: NITISINONA 10 MG, NITISOR® 10 MG CAPSULAS
  4. Drug

    Fluoxetine

    go.drugbank.com/drugs/DB00472
    ApprovedInvestigationalVet approved

    Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).

    Mixtures: TARGET 6 MG /50 MG KAPSUL, 90 ADET, TARGET 6 MG /50 MG KAPSUL, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  5. Drug

    Darifenacin

    go.drugbank.com/drugs/DB00496
    ApprovedInvestigational

    Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: Darifenacin 15 mg, ENABLEX 15 MG
  6. Drug

    Fluvoxamine

    go.drugbank.com/drugs/DB00176
    ApprovedInvestigational

    As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. … Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: FAVERIN 100 MG, FAVERIN 50 MG
  7. Drug

    Piroxicam

    go.drugbank.com/drugs/DB00554
    ApprovedInvestigational

    A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsProducts: PIROXICAM AL 10, BREXIN L
  8. Drug

    Activated charcoal

    go.drugbank.com/drugs/DB09278
    ApprovedInvestigational

    It works by binding to the poison in the gastric contents in a reversible fashion thus may be adminstered together with a cathartic to reduce the small intestine transit time. … It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high affinity for various substances

    Mixtures: İNTESTİNOL 59,4 MG/21,3 MG/71,1 MG KAPLI TABLET, 120 ADET, İNTESTİNOL 59,4 MG/21,3 MG/71,1 MG KAPLI TABLET, 60 ADETCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Canagliflozin

    go.drugbank.com/drugs/DB08907
    ApprovedInvestigational

    Canagliflozin, also known as _Invokana_, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise … It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 for a second indication of reducing the risk of cardiovascular events in patients diagnosed with type

    Mixtures: VOKANAMET 150 MG/500 MG, FILM-COATED TABLETS 150 MG / 500 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Hydrocortisone

    go.drugbank.com/drugs/DB00741
    ApprovedInvestigationalVet approved

    Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.

    Synonyms: Reichstein's substance MInternational brands: Ala-Scalp