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Ulimorelin
go.drugbank.com/drugs/DB12128InvestigationalUlimorelin is a novel small molecule ghrelin agonist being developed by Tranzyme Pharma as a first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility of
MLN-977
go.drugbank.com/drugs/DB05431ExperimentalMLN-977 is a small molecule compound that inhibits the production of leukotrienes, especially 5-lipoxygenase. It is developed by PharmaEngine to treat asthma and chronic obstructive pulmonary disease.
Biropepimut-S
go.drugbank.com/drugs/DB14816InvestigationalBiropepimut-S is under investigation in clinical trial NCT02873819 (Safety and Efficacy Study of GL-0817 (With Cyclophosphamide) for the Prevention of Recurrence of Squamous Cell Carcinoma of the Oral
Ibrigampar
go.drugbank.com/drugs/DB05490InvestigationalT131 is not structurally related to the thiazolidinedione class of PPARg agonists, which includes Actos and Avandia. … T131 is a selective modulator of PPARg (peroxisome proliferator activated receptor gamma), a receptor involved in regulating the body’s ability to respond to insulin.
Squalene
go.drugbank.com/drugs/DB11460ApprovedInvestigationalVet approvedWithdrawnIt is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol. It is not susceptible to lipid peroxidation and provides skin protection.
Products: Natural Life Squalene 1000 mgEtifoxine
go.drugbank.com/drugs/DB08986ApprovedWithdrawnIt does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiazepines. It is more effective than lorazepam as an anxiolytic, and has fewer side effects.
Equilenin
go.drugbank.com/drugs/DB03515ExperimentalIt has a total of five double bonds in the A- and B-ring. High concentration of equilenin is found in the urine of pregnant mares.
ARX201
go.drugbank.com/drugs/DB05082InvestigationalARX201 (PEG-ahGH) is a recombinant form of human growth hormone that has been modified using Ambrx’s patented ReCODE™ technology to achieve precise spatial positioning of the site of polyethylene glycol … (PEG) attachment to human growth hormone, by biosynthetic incorporation of a chemically unique amino acid (ahGH).
NTx-265
go.drugbank.com/drugs/DB05649Investigationalof death worldwide. … NTx-265 is a combination of two currently marketed large molecules designed to stimulate the growth and differentiation of neural stem cells in adults who have suffered a stroke – the second leading cause
EGS21
go.drugbank.com/drugs/DB05056Experimentalvarious immune mediated diseases, such as Crohn's disease, hepatitis, non-alcoholic steatohepatitis (NASH) or fatty liver and HIV. … been shown by Enzo scientists and collaborators to act as an anti-inflammatory agent in animal model systems, and therefore is being evaluated as an important candidate drug in the treatment of