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ZEN-3694
go.drugbank.com/drugs/DB22031InvestigationalZEN-3694 is under investigation in clinical trial NCT04840589 (Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors).
Synonyms: BETi ZEN-3694Roledumab
go.drugbank.com/drugs/DB16317InvestigationalRoledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab in Rhd-negative Pregnant Women Carrying an Rhd-positive Foetus).
Tesnatilimab
go.drugbank.com/drugs/DB16377InvestigationalTesnatilimab is under investigation in clinical trial NCT04655807 (A Study of JNJ-64304500 as Add-on Therapy in Participants With Active Crohn's Disease).
VX-702
go.drugbank.com/drugs/DB05470InvestigationalIn the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Polaprezinc
go.drugbank.com/drugs/DB09221InvestigationalIt was determined that polaprezinc may be effective in pressure ulcer treatment [A31856]. … It is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1308].
Branaplam
go.drugbank.com/drugs/DB14918InvestigationalBranaplam is under investigation in clinical trial NCT02268552 (An Open Label Study of LMI070 (Branaplam) in Type 1 Spinal Muscular Atrophy (SMA)).
Firtecan pegol
go.drugbank.com/drugs/DB14953InvestigationalFirtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer).
Dimethyltryptamine
go.drugbank.com/drugs/DB01488IllicitInvestigationalAn N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. … It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others.
Synonyms: N,N-dimethyltryptamine, N,N-dimethyl-1H-indole-3-ethylamineLyme disease vaccine (recombinant OspA)
go.drugbank.com/drugs/DB00045ApprovedWithdrawnLipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant. … Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli.
Sulodexide
go.drugbank.com/drugs/DB06271ApprovedInvestigationalWithdrawnSulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).