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β-Methylfentanyl
go.drugbank.com/drugs/DB09171ExperimentalIllicitβ-Methylfentanyl is an analgesic of the _opioid_ class. It is an analog of the potent opioid, fentanyl.
KER-047
go.drugbank.com/drugs/DB19111InvestigationalKER-047 is under investigation in clinical trial NCT05927012 (A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (
Gevokizumab
go.drugbank.com/drugs/DB12119InvestigationalGevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. … Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others.
SYNB1020
go.drugbank.com/drugs/DB17667Investigationaldiscontinued further development of SYNB1020 to treat hyperammonemia due to a lack of evidence of ammonia-lowering activities by SYNB1020 in a Phase 1b/2a study. … SYNB1020 is an engineered strain of _Escherichia coli_ Nissle 1917 developed by Synlogic Inc.
TBI-223
go.drugbank.com/drugs/DB18911InvestigationalTBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis).
Arazasetron
go.drugbank.com/drugs/DB19237InvestigationalArazasetron is currently under investigation in clinical trial NCT05258773 (Evaluation of the Presence of SENS-401 in the Perilymph).
Phosphonothreonine
go.drugbank.com/drugs/DB02482ExperimentalThe phosphoric acid ester of threonine. Used as an identifier in the analysis of peptides, proteins, and enzymes. [PubChem]
IDM-2
go.drugbank.com/drugs/DB05293ExperimentalIDM-2 is composed of Monocyte-derived Activated Killer (MAK) cells.
Galidesivir
go.drugbank.com/drugs/DB11676Investigational[L12039,L12084] Phase 1 clinical trials have begun to determine the safety of this drug in humans. … [L12042] Because of its activity against other coronaviruses, it may be studied as a potential therapy for COVID-19.
Elacytarabine
go.drugbank.com/drugs/DB05494InvestigationalElacytarabine is a fatty acid derivative of [cytarabine], an approved cytotoxic cancer drug. Cytarabine has limitations such as minimal uptake in solid tumours and is only used to treat leukaemia. … Elacytarabine is a patented new chemical entity of the nucleoside analog class, with improved biological properties and the potential to treat solid tumours such as non-small cell lung cancer, malignant