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Displaying results 6271 - 6280 of 10000 in total
  1. Drug

    Theanine

    go.drugbank.com/drugs/DB12444
    Investigational

    Theanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD).

    Synonyms: N(5)-ethyl-L-glutamine, N-ethyl-L-glutamine
  2. Drug

    ALZ-507

    go.drugbank.com/drugs/DB33980
    Experimental

    ALZ-507 is a small molecule drug. ALZ-507 is under investigation in clinical trial NCT07824271 (Safety and Pharmacokinetics of ALZ-507 in Healthy Elderly Adults).

  3. Drug

    L-cysteic acid

    go.drugbank.com/drugs/DB03661
    Experimental

    L-cysteic acid is a beta-sulfoalanine. It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized with permanganate. … It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather.

    Synonyms: 3-sulfo-L-alanine, 2-Amino-3-sulfopropionic acid
  4. Drug

    Alofanib

    go.drugbank.com/drugs/DB20918
    Investigational

    Alofanib is a small molecule drug. The usage of the INN stem '-anib' in the name indicates that Alofanib is a angiogenesis inhibitor. … Alofanib is under investigation in clinical trial NCT04071184 (Study of Alofanib in Patients With Metastatic Gastric Cancer). Alofanib has a monoisotopic molecular weight of 413.07 Da.

  5. Drug

    Zanidatamab zovodotin

    go.drugbank.com/drugs/DB15472
    Experimental

    According to Zymeworks, "ZW49 (zanidatamab zovodotin) is a bispecific anti-HER2 ADC that is based on the same antibody framework as [ZW25] but armed with a cytotoxic payload." … [L8234] It is being investigated for several indications characterized by HER2 expression including breast and gastric cancers that have progressed or are refractory to existing HER2-targeted therapies

    Synonyms: anti-HER2 x HER2 ADC
  6. Drug

    Telratolimod

    go.drugbank.com/drugs/DB19590
    Investigational

    Telratolimod is a small molecule drug. The usage of the INN stem '-tolimod' in the name indicates that Telratolimod is a toll-like receptor (TLR) agonist. … Telratolimod is under investigation in clinical trial NCT06680479 (Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy

  7. Drug

    Icenticaftor

    go.drugbank.com/drugs/DB21466
    Investigational

    Icenticaftor is a small molecule drug. … The usage of the INN stem '-caftor' in the name indicates that Icenticaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Rezivertinib

    go.drugbank.com/drugs/DB21471
    Investigational

    Rezivertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Rezivertinib is a epidermal growth factor receptor (EGFR) inhibitor. … Rezivertinib has a monoisotopic molecular weight of 486.24 Da.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    Tuxobertinib

    go.drugbank.com/drugs/DB21508
    Investigational

    Tuxobertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Tuxobertinib is a epidermal growth factor receptor (EGFR) inhibitor. … Tuxobertinib is under investigation in clinical trial NCT04209465 (A Study of BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.).

  10. Drug

    Linvencorvir

    go.drugbank.com/drugs/DB21544
    Investigational

    Linvencorvir is a small molecule drug. The usage of the INN stem '-corvir' in the name indicates that Linvencorvir is a core protein (Cp) inhibitor. … Linvencorvir is under investigation in clinical trial NCT04225715 (A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B).

    Categories: Heterocyclic Compounds, 1-Ring