Linvencorvir

DB21544InvestigationalSmall molecule

Linvencorvir is a small molecule drug. The usage of the INN stem '-corvir' in the name indicates that Linvencorvir is a core protein (Cp) inhibitor. Linvencorvir is under investigation in... Linvencorvir is under investigation in clinical trial NCT04225715 (A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B).

Mechanism: Pharmacologically active on Capsid protein
Curator reviewed
Formula / weight: C₂₉H₃₅FN₆O₅S · 598.69 g/mol (avg)
Code names: RG-7907 · RO-7049389

Resolves to

Compound

UNII74UDO8415OCAS1808248-05-6ChEMBLCHEMBL5095071ChEBI758655PubChem118354396

Structure

InChIKeyYLJBFYZGSKMBEZ-MBSDFSHPSA-NSMILES[H][C@]12CN(CC(C)(C)C(O)=O)C(=O)N1CCN(CC1=C([C@@H](N=C(N1)C1=NC=CS1)C1=C(C)C(F)=CC=C1)C(=O)OCC)C2

Targets

P03148C

Transporters

Q9Y6L6SLCO1B1Q9NPD5SLCO1B3

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2TransportersSubstrate / inhibitor direction, not just membership

Listed above

5Clinical trialsPhase, status and sponsor resolved per trial

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with Linvencorvir, and which of those have an active Phase 3 trial?

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