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Afimetoran
go.drugbank.com/drugs/DB16580Investigational[L32018, L32023] It is also is under investigation in clinical trial NCT04269356 (Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986256 in Healthy Male
VB2-011
go.drugbank.com/drugs/DB05411ExperimentalAccording to some preclinical studies, it has a potential to inhibit tumour growth in various cancers including lymphoma and melanoma. … This drug includes the parent IgM (H11 IgM) and a recombinant IgG version (H11 IgG).
Ladostigil
go.drugbank.com/drugs/DB16213InvestigationalLadostigil is under investigation in clinical trial NCT01429623 (A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment).
Synonyms: Tv-3326 free baseAstegolimab
go.drugbank.com/drugs/DB16386InvestigationalAstegolimab is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Indoprofen
go.drugbank.com/drugs/DB08951ApprovedWithdrawnFollowing reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
Tetrathiomolybdate
go.drugbank.com/drugs/DB05088InvestigationalIt is also developed for fibrotic disorders based upon the rationale that the fibrotic disease process is dependent upon the availability of free copper in the body. … COPREXA has completed pivotal clinical trials for the treatment of neurologic Wilson's disease.
NTx-265
go.drugbank.com/drugs/DB05649InvestigationalNTx-265 is a combination of two currently marketed large molecules designed to stimulate the growth and differentiation of neural stem cells in adults who have suffered a stroke – the second leading cause … It is also investigating use of the compound for neurodegenerative disorders, such as Huntington’s disease and Alzheimer’s disease.
Nevadistinel
go.drugbank.com/drugs/DB21632InvestigationalThe usage of the INN stem '-stinel' in the name indicates that Nevadistinel is a N-methyl-D-aspartate (NMDA) receptor co-agonist. … Nevadistinel is under investigation in clinical trial NCT04148391 (NYX-458 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's Disease or Lewy Body Dementia (Cognition, Memory
NB-001
go.drugbank.com/drugs/DB12716InvestigationalNB-001 has been investigated for the treatment of Recurrent Herpes Labialis.
SJG-136
go.drugbank.com/drugs/DB11965InvestigationalSJG-136 has been used in trials studying the treatment of Recurrent Fallopian Tube Cancer, Secondary Acute Myeloid Leukemia, de Novo Myelodysplastic Syndromes, Recurrent Ovarian Epithelial Cancer, and