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Displaying results 621 - 630 of 10000 in total
  1. Drug

    Desipramine

    go.drugbank.com/drugs/DB01151
    Approved

    TCAs also block histamine-H<sub>1</sub> receptors, &alpha;<sub>1</sub>-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred … In depressed individuals, desipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.

    Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, Serotonin 5-HT2 Receptor AntagonistsSynonyms: N-(3-methylaminopropyl)iminobibenzyl, 5-(γ-methylaminopropyl)iminodibenzyl
  2. Drug

    Emivirine

    go.drugbank.com/drugs/DB08188
    Investigational

    Emivirine has been used in trials studying the treatment of HIV Infections.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 6-benzyl-1-(ethoxymethyl)-5-(1-methylethyl)uracil, 1-(ethoxymethyl)-5-(1-methylethyl)-6-(phenylmethyl)pyrimidine-2,4(1H,3H)-dione
  3. Drug

    Prochlorperazine

    go.drugbank.com/drugs/DB00433
    ApprovedInvestigationalVet approved

    Although newer antiemetic agents such as 5-HT3 antagonists are more heavily promoted, prochlorperazine is still widely used in nausea and vomiting.[L6640] … [label] It mainly works by depressing the chemoreceptor trigger zone and blocking D2 dopamine receptors in the brain. It was shown to also block histaminergic, cholinergic and noradrenergic receptors.

    Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazine, Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine
  4. Drug

    Lodoxamide

    go.drugbank.com/drugs/DB06794
    Approved

    Lodoxamide is a mast-cell stabilizer for topical administration into the eye. … Mast-cell stabilizers, first one approved being cromolyn sodium, are used in treatment of ocular hypersensitivity reactions such as vernal conjunctivitis.

    Synonyms: N,N'-(2-chloro-5-cyano-m-phenylene)dioxamateProducts: THILOMIDE GÖZ DAMLASI, 5 ML, ALOMİDE % 0.1 GÖZ DAMLASI, ÇÖZELTİ, 5 ML
  5. Drug

    Bacillus coagulans

    go.drugbank.com/drugs/DB19246
    Investigational

    Synonyms: Bacillus coagulans hammer, 1915 emend. de clerck et al., 2004
  6. Drug

    1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One

    go.drugbank.com/drugs/DB02873
    Experimental

    Synonyms: 1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One
  7. Drug

    1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone

    go.drugbank.com/drugs/DB07342
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring, Heme Oxygenase-1, antagonists & inhibitorsSynonyms: 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone
  8. Drug

    Tamsulosin

    go.drugbank.com/drugs/DB00706
    ApprovedInvestigational

    Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common. … [Label] Other alpha-1 adrenoceptor antagonists developed in the 1980s were less selective and more likely to act on the smooth muscle of blood vessels, resulting in hypotension.

    Synonyms: (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide, (R)-(−)-tamsulosinInternational brands: Harnal D
  9. Drug

    Zolmitriptan

    go.drugbank.com/drugs/DB00315
    ApprovedInvestigational

    Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine. … It is currently available in both tablet and nasal spray forms.[L12978]

    Categories: Monoamine Oxidase A Substrates, Heterocyclic Compounds, 1-RingSynonyms: 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one, (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
  10. Drug

    Influenza B virus B/Wisconsin/1/2010 recombinant hemagglutinin antigen

    go.drugbank.com/drugs/DB10775
    ApprovedInvestigationalWithdrawn

    Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses.

    Synonyms: Influenza B virus vaccine, B-Wisconsin-1-2010-like virus, Influenza B virus B/Wisconsin/1/2010 recombinant hemagglutinin antigen