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Cavia porcellus skin
go.drugbank.com/drugs/DB10416ApprovedCavia porcellus skin or pelt is used in allergenic testing.
Mixtures: Guinea Pig Hair and EpitheliaSultopride
go.drugbank.com/drugs/DB13273ApprovedSultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics [L5626].
Categories: Benzamides and benzamide derivativesQuinupramine
go.drugbank.com/drugs/DB13246ApprovedQuinupramine has been approved in France under the brand name Kinupril, as an antidepressant [A175003].
ATG003
go.drugbank.com/drugs/DB05069InvestigationalATG003, a novel anti-angiogenic drug candidate and a formulation of mecamylamine, is currently in clinical development for neovascular age-related macular degeneration.
Col-118
go.drugbank.com/drugs/DB05778InvestigationalIt is a believed to reduce erythema by constricting enlarged blood vessels in facial tissue. … Col-118 is a unique formulation and presentation of Brimonidine, which is a selective alpha-2 adrenergic receptor agonist.
Mevastatin
go.drugbank.com/drugs/DB06693ExperimentalThe compound was proposed to bind to the reductase enzyme and was named compactin. … Mevastatin is a pro-drug that is activated by <i>in vivo</i> hydrolysis of the lactone ring. It has served as one of the lead compounds for the development of the synthetic compounds used today.
TGAAC94
go.drugbank.com/drugs/DB06175InvestigationalIt was under investigation in clinical trials to treat Inflammatory Arthritis. In 2007, one patient participating in the clinical trial died and the trial was placed on clinical hold by the FDA. … The Health Recombinant DNA Advisory Committee (RAC) concluded that a possible role of the gene transfer in this clinical course could not definitively be excluded due to the lack of data. [A264038]
Tunicamycin
go.drugbank.com/drugs/DB13172ExperimentalTunicamycin is produced by Streptomyces clavuligerus and Streptomyces lysosuperficus bacteria along with several other species. … Tunicamycin blocks N-linked glycosylation (N-glycans) resulting in cell cycle arrest at the G1 phase in human cells. It is used as an experimental tool to induce unfolded protein response.
Categories: Nucleic Acids, Nucleotides, and NucleosidesIC41
go.drugbank.com/drugs/DB05776InvestigationalIC41 is a therapeutic peptide vaccine. It is being devloped by Intercell AG for the treatment of hepatitis C. … The vaccine consists of five synthetic peptides (IPEP83, 84, 87, 89,1426) harboring HCV CD4 and CD8 T-cell epitopes and the synthetic adjuvant poly-L-arginine.
Oxibendazole
go.drugbank.com/drugs/DB04910ExperimentalVet approvedOxibendazole is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.
Synonyms: Methyl 5-n-propoxy-2-benzimidazole carbamate