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Displaying results 6291 - 6300 of 10000 in total
  1. Drug

    ChulaCov19 mRNA vaccine

    go.drugbank.com/drugs/DB16445
    Experimental

    The ChulaCov19 vaccine is mRNA-based and was developed in Thailand’s Chulalongkorn University in collaboration with the University of Pennsylvania in the US[L30673, L30678]. … Pre-clinical studies in mice and monkeys showed evidence that the vaccine facilitates an impressive generation of neutralizing antibodies[L30678].

  2. Drug

    RO7296682

    go.drugbank.com/drugs/DB17531
    Investigational

    RO7296682 is under investigation in clinical trial NCT04642365 (A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors. … RO7296682 is a monoclonal antibody against CD25 (IL-2R alpha) expressed on tumour-infiltrating regulatory T (T<sub>reg</sub>) cells.

  3. Drug

    Luveltamab tazevibulin

    go.drugbank.com/drugs/DB17563
    Investigational

    [A257414] It is under investigation in clinical trial NCT05200364 (A Study of STRO-002, an Anti-folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer

  4. Drug

    Nelistotug

    go.drugbank.com/drugs/DB19334
    Investigational

    Nelistotug is under investigation in clinical trial NCT06062420 (A Platform Study of Novel Immunotherapy Combinations as First-line Treatment in Participants With PD-L1 Positive Recurrent/metastatic Squamous … Cell Carcinoma of the Head and Neck- GALAXIES H&N-202).

  5. Drug

    Alpibectir

    go.drugbank.com/drugs/DB21561
    Investigational

    Alpibectir is under investigation in clinical trial NCT06748937 (A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination With Ethionamide). … Alpibectir has a monoisotopic molecular weight of 332.1 Da.

  6. Drug

    Ceperognastat

    go.drugbank.com/drugs/DB21591
    Investigational

    Ceperognastat is under investigation in clinical trial NCT05063539 (A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease). … Ceperognastat has a monoisotopic molecular weight of 383.14 Da.

  7. Drug

    Ranosidenib

    go.drugbank.com/drugs/DB21727
    Investigational

    Ranosidenib is a small molecule drug. Ranosidenib is under investigation in clinical trial NCT06387069 (A Study to Evaluate HMPL-306 in Patients With IDH1- and IDH2-mutated Acute Myeloid Leukemia). … Ranosidenib has a monoisotopic molecular weight of 453.12 Da.

  8. Drug

    Puromycin

    go.drugbank.com/drugs/DB08437
    Experimental

    Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. … Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting in significant cell death at appropriate doses.

  9. Drug

    SVV-001

    go.drugbank.com/drugs/DB06129
    Investigational

    SVV-001 is investigated for use/treatment in cancer/tumors and lung cancer. SVV-001 is a solid. … SVV-001 (Seneca Valley Virus) is a novel native picornavirus being developed as a systemically deliverable oncolytic virus for treatment of human cancers with neuroendocrine features.

  10. Drug

    Methylmethionine chloride

    go.drugbank.com/drugs/DB13250
    Experimental

    It is also called "Vitamin U", but it is not a true vitamin. … Methylmethionine chloride may be useful in helping the healing of gastric ulcers. In Japan, it is used as an over the counter product for gastrointestinal health support.