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Displaying results 6301 - 6310 of 10000 in total
  1. Drug

    S-777469

    go.drugbank.com/drugs/DB16321
    Investigational

    S-777469 is under investigation in clinical trial NCT00703573 (A Randomized, Double-blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis).

  2. Drug

    Bremzalerbart

    go.drugbank.com/drugs/DB19417
    Investigational

    Bremzalerbart is under investigation in clinical trial NCT06602739 (A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen

  3. Drug

    Atisnolerbart

    go.drugbank.com/drugs/DB19418
    Investigational

    Atisnolerbart is under investigation in clinical trial NCT06602739 (A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen

  4. Drug

    ABP-700

    go.drugbank.com/drugs/DB15411
    Investigational

    ABP-700 is under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy

    Categories: GABA-A Receptor Agonists
  5. Drug

    L-lysyl-l-arginine

    go.drugbank.com/drugs/DB19436
    Investigational

    L-lysyl-l-arginine is under investigation in clinical trial NCT03972488 (Study to Evaluate the Efficacy and Safety of Lutathera in Patients With Grade 2 and Grade 3 Advanced GEP-NET).

  6. Drug

    TPMPA

    go.drugbank.com/drugs/DB16754
    Experimental

    [A245308,A245313] TPMPA is used as a pharmacological probe for the investigation of GABA<sub>C</sub> receptor function.[A245313] … [A245303] GABA<sub>C</sub> receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut

  7. Drug

    Cinalukast

    go.drugbank.com/drugs/DB00587
    Experimental

    Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. … Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.

    Synonyms: 3'-((E)-2-(4-cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid
  8. Drug

    Formebolone

    go.drugbank.com/drugs/DB01569
    IllicitInvestigational

    It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened for in athletes. … It has been used experimentally in the treatment of growth retardation, and has been noted to increase bone mass.

  9. Drug

    SAR445136

    go.drugbank.com/drugs/DB17708
    Investigational

    [A259063] It was formerly investigated for the treatment of beta-thalassemia, and it is currently being investigated for the treatment of sickle cell disease.[L46148] … It consists of autologous CD34+ hematopoietic stem precursor cells (HSPC) modified ex vivo by zinc finger nucleases (ZFN) that target the BCL11A gene erythroid-specific enhancer (ESE) to increase endogenous

  10. Drug

    MVC-COV1901

    go.drugbank.com/drugs/DB15854
    Investigational

    The vaccine candidate contains a perfusion form of the SARS-Cov2 recombinant spike protein. … As of September 2020, the vaccine candidate is in Phase 1 clinical trials to assess its safety and immunogenicity (NCT04487210).