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DB16754ExperimentalSmall molecule
TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABAC receptors (also known as GABA-ρ or GABAA-ρ receptors). GABAC receptors are found primarily in the retina, although they may be present... GABAC receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut.
- Formula / weight
- C6H12NO2P · 161.141 g/mol (avg)
Resolves to
Structure
InChIKey
MFUKVPOVVKKLRQ-UHFFFAOYSA-NSMILESCP(O)(=O)C1=CCNCC1What you can answer from here — as of April 02, 2025
3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
Which drugs share a target with TPMPA, and which of those have an active Phase 3 trial?