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Pexiganan
go.drugbank.com/drugs/DB16293InvestigationalPexiganan is under investigation in clinical trial NCT01594762 (Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers).
beta-Sitosterol
go.drugbank.com/drugs/DB14038InvestigationalActive fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity.
Synonyms: (3β)-Stigmast-5-en-3-ol, (24R)-ethylcholest-5-en-3β-olGo-6976
go.drugbank.com/drugs/DB17029ExperimentalAn inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]
PI-103
go.drugbank.com/drugs/DB17046ExperimentalPI-103 is an inhibitor of p110α of class I PI3K.[A253092]
APG-157
go.drugbank.com/drugs/DB18683InvestigationalNutraceuticalAPG-157 consists of zinflavonoids being investigated for the treatment of cancers.
DTX-101
go.drugbank.com/drugs/DB17699InvestigationalIt was previously investigated for the treatment of hemophilia B; however, the clinical development of DTX-101 was discontinued.[L46103] … DTX-101 is an investigational gene therapy consisting of an adeno-associated virus serotype Rh10 vector encoding the human Factor Ix gene.
Lapyrium
go.drugbank.com/drugs/DB09376ApprovedLapyrium is a quaternary ammonium cation used as a surfactant, antistatic agent, and biocide in various cosmetic products . It is commonly found formulated as lapyrium chloride.
GB-13
go.drugbank.com/drugs/DB18387ExperimentalGB-13 is a genetically engineered recombinant protein consisting of an IL13Ra2-targeted genetically engineered mutant of IL-13 and PE4E, a derivative of Pseudomonas exotoxin A.
DDP-225
go.drugbank.com/drugs/DB05642InvestigationalNoradrenaline and serotonin are neurotransmitters that are known to be involved in the control of the gastrointestinal system. … The unique combination of noradrenaline reuptake inhibition and 5-HT3 antagonism in one orally delivered compound represents a novel approach to treating IBS-d and other functional GI diseases.
Pardoprunox
go.drugbank.com/drugs/DB12061InvestigationalPardoprunox has been used in trials studying the treatment of Early Stage Parkinson's Disease and Advanced Stage Parkinson's Disease.