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Macitentan
go.drugbank.com/drugs/DB08932ApprovedInvestigationalMacitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013. … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October 2021 for the treatment of PAH.[L39105] It was subsequently approved by the FDA in March 2024.
Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTASCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingLetosteine
go.drugbank.com/drugs/DB08939ExperimentalLetosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.
Kebuzone
go.drugbank.com/drugs/DB08940InvestigationalKebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.
Mixtures: Rheumesser 3 ml - AmpullenCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingIndoprofen
go.drugbank.com/drugs/DB08951ApprovedWithdrawnA drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-RingIbuproxam
go.drugbank.com/drugs/DB08955ApprovedWithdrawnIbuproxam is a non steroidal anti-inflammatory drug (NSAID).
Categories: Non COX-2 selective NSAIDSSynonyms: p-Isobutylhydratropohydroxamic acidGlibornuride
go.drugbank.com/drugs/DB08962ApprovedWithdrawnGlibornuride is a sulfonylurea-type anti-diabetic drug.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesFluprednidene
go.drugbank.com/drugs/DB08970ExperimentalFluprednidene is a corticosteroid.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersFlumequine
go.drugbank.com/drugs/DB08972ApprovedWithdrawnFlumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingFenbufen
go.drugbank.com/drugs/DB08981ApprovedFenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. … Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.
Categories: Non COX-2 selective NSAIDSSynonyms: 4-(4-Biphenylyl)-4-oxobutyric acid, 3-(4-Phenylbenzoyl)propionic acidEtofibrate
go.drugbank.com/drugs/DB08983ExperimentalEtofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin.