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Displaying results 6321 - 6330 of 10000 in total
  1. Drug

    Benclonidine

    go.drugbank.com/drugs/DB19610
    Experimental

    Benclonidine is a small molecule drug. The usage of the INN stem '-nidine' in the name indicates that Benclonidine is a a2 adrenoreceptor agonist. … Benclonidine has a monoisotopic molecular weight of 333.04 Da.

  2. Drug

    Flutonidine

    go.drugbank.com/drugs/DB21438
    Experimental

    Flutonidine is a small molecule drug. The usage of the INN stem '-nidine' in the name indicates that Flutonidine is a a2 adrenoreceptor agonist. … Flutonidine has a monoisotopic molecular weight of 193.1 Da.

  3. Drug

    Povafonidine

    go.drugbank.com/drugs/DB21470
    Experimental

    Povafonidine is a small molecule drug. The usage of the INN stem '-nidine' in the name indicates that Povafonidine is a a2 adrenoreceptor agonist. … Povafonidine has a monoisotopic molecular weight of 215.12 Da.

  4. Drug

    MBO7133

    go.drugbank.com/drugs/DB04999
    Experimental

    MB07133 is a HepDirect prodrug of an activated form of cytarabine (araC), an anti-cancer drug that is used to treat leukemia but is ineffective against primary liver cancer. … MB07133 uses our HepDirect technology to target a prodrug form of araCMP specifically to the liver.

  5. Drug

    AVI-4557

    go.drugbank.com/drugs/DB05447
    Experimental

    in clearance and an increase in maximal blood concentration (Cmax). … AVI-4557 is an oral antisense compound that selectively inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a liver enzyme responsible for the metabolism or breakdown of approximately half of currently

  6. Drug

    ETC-588

    go.drugbank.com/drugs/DB05456
    Experimental

    Esperion is currently developing ETC-588 as a treatment for patients with acute coronary syndromes. … LUV are capable of transporting excess cholesterol from the vasculature to the liver for eventual elimination as part of the reverse lipid transport (RLT) pathway.

  7. Drug

    TMC-310911

    go.drugbank.com/drugs/DB15623
    Investigational

    TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available [darunavir]. … [L12045,A191643] TMC-310911 is currently being investigated, in combination with other HIV therapies and antivirals, as a potential treatment for COVID-19 caused by SARS-CoV-2.[L12012]

  8. Drug

    Tuparstobart

    go.drugbank.com/drugs/DB19118
    Investigational

    Tuparstobart is under investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-line Treatment in Participants With Pd-l1-positive (CPS

  9. Drug

    Fluorfenidine F-18

    go.drugbank.com/drugs/DB19557
    Experimental

    Fluorfenidine F-18 is a small molecule drug. The usage of the INN stem '-nidine' in the name indicates that Fluorfenidine F-18 is a a2 adrenoreceptor agonist. … Fluorfenidine F-18 has a monoisotopic molecular weight of 382.07 Da.

  10. Drug

    5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine

    go.drugbank.com/drugs/DB08666
    Experimental

    These are aromatic compounds containing at least one benzene ring. This drug targets the protein methionine aminopeptidase. … 5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine is a solid. This compound belongs to the benzene and substituted derivatives.