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Cetrelimab
go.drugbank.com/drugs/DB15421InvestigationalCetrelimab is under investigation in clinical trial NCT03547037 (A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of JNJ-63723283, an Anti-Programmed Cell Death (PD … )-1 Monoclonal Antibody, as Monotherapy or in Combination With Erdafitinib in Japanese Participants With Advanced Solid Cancers).
RO7300490
go.drugbank.com/drugs/DB17535InvestigationalRO7300490 is an investigational Fibroblast Activation Protein-α (FAP) targeted CD40 agonist. … RO7300490 is under investigation in clinical trial NCT04857138 (A Study to Evaluate Safety, Pharmacokinetics and Anti-tumor Activity of RO7300490, as Single Agent or in Combination With Atezolizumab in
Sitaxentan
go.drugbank.com/drugs/DB06268ApprovedWithdrawnIn 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity. … Sitaxentan was marketed under the trade name Thelin for the treatment of pulmonary arterial hypertension (PAH) by Encysive Pharmaceuticals until Pfizer purchased Encysive in February 2008.
Categories: Endothelin Receptor AntagonistsZosuquidar
go.drugbank.com/drugs/DB06191InvestigationalZosuquidar is a compound of antineoplastic drug candidates currently under development. It is now in "Phase 3" of clinical tests in the United States.
SBT-100
go.drugbank.com/drugs/DB17215ExperimentalSBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody (sdAb). … It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma.[L44131,L44136]
Fenspiride
go.drugbank.com/drugs/DB08979InvestigationalFenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. … It is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis
9MW3011
go.drugbank.com/drugs/DB24999InvestigationalThe drug is an anti-TMPRSS6 (Transmembrane Serine Protease 6, also known as Matriptase-2) monoclonal antibody.[L54591, L54596] … 9MW3011 is a biologic drug. 9MW3011 is under investigation in clinical trial NCT06752746 (A Study of Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of 9MW3011 in Patients
Rumex acetosella whole
go.drugbank.com/drugs/DB14166ApprovedWithdrawnRumex acetosella whole allergenic extract is used in allergenic testing.
Rumex crispus top
go.drugbank.com/drugs/DB14167ApprovedWithdrawnRumex crispus top allergenic extract is used in allergenic testing.
Salix nigra bark
go.drugbank.com/drugs/DB14169ApprovedWithdrawnSalix nigra bark allergenic extract is used in allergenic testing.