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anti-OX40 antibody BMS 986178
go.drugbank.com/drugs/DB15773InvestigationalA macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 antibody.
Dopastatin
go.drugbank.com/drugs/DB16144InvestigationalDopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas).
Nendratareotide uzatansine
go.drugbank.com/drugs/DB18351InvestigationalNendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Synonyms: Peptide-drug conjugate combining [(Tyr3,Cys8) octreotate amide] and N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl) maytansineECT204
go.drugbank.com/drugs/DB18605InvestigationalECT204 is an autologous T-cell therapy whereby T cells are genetically modified to target tumor-specific antigens.
Tamnorzatinib
go.drugbank.com/drugs/DB19201InvestigationalTamnorzatinib is under investigation in clinical trial NCT03176277 (A Study of ONO-7475 in Patients With Acute Leukemias).
Synonyms: 3-quinolinecarboxamide, n-(5-((6,7-dimethoxy-4-quinolinyl)oxy)-2-pyridinyl)-1,2,5,6,7,8-hexahydro-2,5-dioxo-1-phenyl-, N-(5-((6,7-dimethoxyquinolin-4-yl)oxy)pyridin-2-yl)-2,5-dioxo-1-phenyl-1,2,5,6,7,8-hexahydroquinoline-3-carboxamideAvasopasem manganese
go.drugbank.com/drugs/DB16354Investigational[L27246, L27256] This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19.
Rogaratinib
go.drugbank.com/drugs/DB15078InvestigationalRogaratinib is under investigation in clinical trial NCT03762122 (Rogaratinib in Patients With Advanced Pretreated Squamous-cell Non-small Cell Lung Cancer (SQCLC)).
Uridine monophosphate
go.drugbank.com/drugs/DB03685InvestigationalA uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Guanosine-5'-Monophosphate
go.drugbank.com/drugs/DB01972ExperimentalA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. [PubChem]
MAHDL01
go.drugbank.com/drugs/DB06270ExperimentalMAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio that improves overall cardiovascular health.