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Displaying results 6391 - 6400 of 10000 in total
  1. Drug

    Gevokizumab

    go.drugbank.com/drugs/DB12119
    Investigational

    Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. … Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others.

  2. Drug

    Omecamtiv Mecarbil

    go.drugbank.com/drugs/DB11816
    Investigational

    Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among

  3. Drug

    Creatinolfosfate

    go.drugbank.com/drugs/DB13071
    Investigational

    COP has been investigated for the treatment of Diabetic Retinopathy. … COP is under investigation for the treatment of Rheumatoid Arthritis, Mature B-Cell Lymphoma, and Noninflammatory Degenerative Joint Disease.

  4. Drug

    Vudalimab

    go.drugbank.com/drugs/DB18833
    Investigational

    Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate

    Synonyms: Immunoglobulin half-ig g1-kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and anti-(homo sapienspdcd1 (programmed cell death 1, pd-1, pd1, cd279)),
  5. Drug

    SYNB1020

    go.drugbank.com/drugs/DB17667
    Investigational

    discontinued further development of SYNB1020 to treat hyperammonemia due to a lack of evidence of ammonia-lowering activities by SYNB1020 in a Phase 1b/2a study. … SYNB1020 is an engineered strain of _Escherichia coli_ Nissle 1917 developed by Synlogic Inc.

  6. Drug

    Farnesol

    go.drugbank.com/drugs/DB02509
    Investigational

    (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) … A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose.

  7. Drug

    Atuveciclib

    go.drugbank.com/drugs/DB20084
    Investigational

    Atuveciclib is under investigation in clinical trial NCT02345382 (Phase I Dose Escalation of BAY1143572 in Subjects With Acute Leukemia). Atuveciclib has a monoisotopic molecular weight of 387.12 Da. … The usage of the INN stem '-ciclib' in the name indicates that Atuveciclib is a cyclin dependant kinase inhibitor.

  8. Drug

    Bavtavirine

    go.drugbank.com/drugs/DB21527
    Investigational

    Bavtavirine is under investigation in clinical trial NCT05585307 (Study of Novel Antiretrovirals in Participants With HIV-1). Bavtavirine has a monoisotopic molecular weight of 416.17 Da. … The usage of the INN stem '-virine' in the name indicates that Bavtavirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI).

  9. Drug

    Cenacitinib

    go.drugbank.com/drugs/DB21735
    Investigational

    Cenacitinib has a monoisotopic molecular weight of 431.15 Da. … The usage of the INN stem '-citinib' in the name indicates that Cenacitinib is a Janus kinase inhibitor.

  10. Drug

    TBI-223

    go.drugbank.com/drugs/DB18911
    Investigational

    TBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis).