Vudalimab

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Vudalimab
DrugBank Accession Number
DB18833
Background

Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate Cancer).

Type
Biotech
Groups
Investigational
Synonyms
  • Anti-PD1 / CTLA4 Bispecific Antibody XmAb20717
  • Anti-pd1/ctla4 bispecific antibody xmab20717
  • Immunoglobulin half-ig g1-kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and anti-(homo sapienspdcd1 (programmed cell death 1, pd-1, pd1, cd279)), monoclonal antibody, bispecific
  • Pd-1 x ctla-4 dual checkpoint inhibitor xmab20717
External IDs
  • Anti-PD-1 / Anti-CTLA-4 XmAb20717
  • ANTI-PD-1/ANTI-CTLA-4 XMAB20717
  • XMAB-20717
  • XmAb20717

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
4I9I5X3Z6N
CAS number
2329669-72-7

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
2Active Not RecruitingTreatmentBile Duct Cancer1somestatusstop reasonjust information to hide
2RecruitingTreatmentCervical Carcinoma / Clear Cell Adenocarcinoma / Endometrial Cancer / Metastatic Castration-Resistant Prostate Cancer (mCRPC) / Ovarian Cancer1somestatusstop reasonjust information to hide
2RecruitingTreatmentLocally Advanced Thyroid Gland Anaplastic Carcinoma / Metastatic Thyroid Gland Anaplastic Carcinoma / Metastatic Thyroid Gland Oncocytic Carcinoma1somestatusstop reasonjust information to hide
2RecruitingTreatmentMetastatic Castration-Resistant Prostate Cancer (mCRPC)1somestatusstop reasonjust information to hide
2SuspendedTreatmentCervical Carcinoma / Extrapulmonary High Grade / Hodgkin's Lymphoma / Microsatellite High Cancers / Neuroendocrine Carcinomas (NEC) / Peritoneal Mesotheliomas / Pleural Mesotheliomas / Small Cell Lung Cancer (SCLC)1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at June 26, 2024 16:04 / Updated at June 27, 2024 01:28