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Displaying results 6401 - 6410 of 10000 in total
  1. Drug

    Cortisone

    go.drugbank.com/drugs/DB14681
    Investigational

    A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. … It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)

    Synonyms: Kendall's compound E, Wintersteiner's compound FCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
  2. Drug

    Gavocabtagene autoleucel

    go.drugbank.com/drugs/DB17367
    Investigational

    which, upon expression, is incorporated into the endogenous T cell receptor (TCR) complex. … Gavocabtagene autoleucel is a novel cell therapy consisting of autologous genetically engineered T cells expressing a single-domain antibody that recognizes human Mesothelin, fused to the CD3-epsilon subunit

  3. Drug

    D2C7 immunotoxin

    go.drugbank.com/drugs/DB17540
    Investigational

    D2C7 immunotoxin (D2C7-IT) is an investigational dual-specific monoclonal antibody targeting EGFRwt and EGFRvIII with a genetically engineered form of the _Pseudomonas exotoxin_, PE38-KDEL. … D2C7-IT is under investigation in clinical trial NCT04160494 (D2C7-IT With Atezolizumab for Recurrent Gliomas).

  4. Drug

    Thalagen

    go.drugbank.com/drugs/DB17714
    Experimental

    Thalagen is a branded product developed by San Rocco Therapeutics. … It is being investigated for the treatment of beta-thalassemia.[L46168]

  5. Drug

    R1626

    go.drugbank.com/drugs/DB05060
    Experimental

    R1626 is one of a new class of hepatitis C therapies called polymerase inhibitors. … It achieves significant reductions in viral load in chronic hepatitis C patients infected with the difficult to treat genotype 1 virus. R1626 is very effective in inhibiting viral replication

  6. Drug

    CR002

    go.drugbank.com/drugs/DB05139
    Investigational

    This is a novel therapeutic approach to treat kidney inflammation. … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation.

    Synonyms: Human monoclonal antibody against platelet-derived growth factor D
  7. Drug

    5-(5-(4-(4,5-dihydro-2-oxazoly)phenoxy)pentyl)-3-methyl osoxazole

    go.drugbank.com/drugs/DB08720
    Experimental

    5-(5-(4-(4,5-dihydro-2-oxazoly)phenoxy)pentyl)-3-methyl osoxazole is a solid. This compound belongs to the phenol ethers. … These are aromatic compounds containing an ether group substituted with a benzene ring. This drug is known to target genome polyprotein.

    Synonyms: 5-(5-(4-(4,5-dihydro-2-oxazoly)phenoxy)pentyl)-3-methyl osoxazole
  8. Drug

    (4R)-limonene

    go.drugbank.com/drugs/DB08921
    Investigational

    As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant … Limonene is common in cosmetic products.

    Synonyms: (+)-(R)-Limonene, (R)-(+)-limonene
  9. Drug

    Bevurogant

    go.drugbank.com/drugs/DB21507
    Experimental

    Bevurogant is a small molecule drug. … The usage of the INN stem '-rogant' in the name indicates that Bevurogant is a retinoic acid receptor-related orphan receptor gamma (RORY) antagonist and inverse agonist.

  10. Drug

    Isospaglumic acid

    go.drugbank.com/drugs/DB19650
    Investigational

    Isospaglumic acid is a small molecule drug. … Isospaglumic acid has a monoisotopic molecular weight of 304.09 Da.

    Synonyms: N-acetylaspartylglutamic acid