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AZD-8186
go.drugbank.com/drugs/DB15029InvestigationalBe Removed by Surgery). … AZD-8186 is under investigation in clinical trial NCT03218826 (PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot
VIR-5818
go.drugbank.com/drugs/DB28582InvestigationalVIR-5818 is under investigation in clinical trial NCT05356741 (To Access the Safety and Effects of Intravenous Administration of VIR-5818 Alone and in Combination With Pembrolizumab in Adult Participants … With Locally Advanced or Metastatic HER2-Expressing Cancers).
Mesmulogene ancovacivec
go.drugbank.com/drugs/DB06584InvestigationalVaccination with MVA-MUC1-IL2 vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) responses against tumor cells expressing MUC1, a tumor associated antigen, … Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective strain incapable of virion assembly and exerts potent immunostimulatory activity against antigens
TH0318
go.drugbank.com/drugs/DB05145ExperimentalTH0318 is a stabilized analogue of human GLP-1 (glucagon-like peptide-1) under investigation for the treatment of type 2 diabetes.
LV-SMENP Vaccine
go.drugbank.com/drugs/DB15804ExperimentalThis vaccine is also administered with antigen-specific cytotoxic T lymphocytes (CTLs). As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials. … LV-SMENP-DC is a vaccine candidate being developed by Shenzhen Geno-Immune Medical Institute that comprises dendritic cells that are modified with lentiviral vector-expressing synthetic minigene which
Dihydroetorphine
go.drugbank.com/drugs/DB01450ExperimentalIllicitCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Heterocyclic Compounds with 4 or More RingsFluprednisolone
go.drugbank.com/drugs/DB09378ApprovedA synthetic glucocorticoid with anti-inflammatory properties.
Categories: Corticosteroids for Systemic UseTeprenone
go.drugbank.com/drugs/DB15955InvestigationalCategories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)MLN3897
go.drugbank.com/drugs/DB06505ExperimentalMLN3897, a novel CCR1 inhibitor, disrupts osteoclast formation and blocks the interaction between multiple myeloma cells and osteoclasts.