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Raseglurant
go.drugbank.com/drugs/DB05070InvestigationalIt is developed for the treatment of GERD, migraine and anxiety.
Tanespimycin
go.drugbank.com/drugs/DB05134InvestigationalTanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90).
Levilimab
go.drugbank.com/drugs/DB16387InvestigationalLevilimab is under investigation in clinical trial NCT04227366 (Study of the Efficacy and Safety of BCD-089 in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis).
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsNurulimab
go.drugbank.com/drugs/DB18946InvestigationalNurulimab is under investigation in clinical trial NCT05732805 (A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-pd-1 Compared to Anti-pd-1 Monotherapy as First-line Treatment in
Categories: prolgolimab and nurulimab, Antineoplastic and Immunomodulating AgentsUridine diphosphate glucose
go.drugbank.com/drugs/DB01861ExperimentalServes as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. … Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.
Categories: Nucleic Acids, Nucleotides, and Nucleosides5-fluorotryptophan
go.drugbank.com/drugs/DB03314Experimental5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy.
Categories: Amino Acids, Peptides, and ProteinsNXN-188
go.drugbank.com/drugs/DB06096InvestigationalNXN-188 is a first-in-class, dual-action small molecule incorporating both neuronal nitric oxide synthase (nNOS) inhibition and 5-HT agonism that is being developed for the treatment of acute migraine.
2G7
go.drugbank.com/drugs/DB18589Experimental2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.
Nitrocefin
go.drugbank.com/drugs/DB11592ExperimentalWhile other detection methods exist, such as PCR, nitrocefin allows for rapid detection using few materials and inexpensive equipment. … Nitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance.
Categories: Indicators and ReagentsAfelimomab
go.drugbank.com/drugs/DB04956ExperimentalAfelimomab (also known as Fab 2 or MAK 195F) is an anti-TNF-α monoclonal antibody. Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents