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ORP-101
go.drugbank.com/drugs/DB16072InvestigationalORP-101 is under investigation in clinical trial NCT04129619 (A Comparison of the Effects of ORP-101 Versus Placebo in Adult Patients With Irritable Bowel Syndrome With Diarrhea (IBS-D)).
IPI-549
go.drugbank.com/drugs/DB16296InvestigationalIPI-549 is under investigation in clinical trial NCT03795610 (Window of Opportunity Study of IPI-549 in Patients With Locally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma).
Cloridarol
go.drugbank.com/drugs/DB13291ExperimentalCloridarol is an experimental medication in the treatment of heart disease, which acts through vasodilation. It was studied for the treatment of coronary insufficiency in Italy in the 1970s [A176222].
Trevogrumab
go.drugbank.com/drugs/DB15159InvestigationalTrevogrumab is under investigation in clinical trial NCT02943239 (Study of Safety, Tolerability, and Pharmacokinetics of REGN2477 Alone and in Combination With REGN1033 in Healthy Postmenopausal Women
DS-2325a
go.drugbank.com/drugs/DB18134InvestigationalDS-2325a is an inhibitor of kallikrein 5 under development for the treatment of Netherton Syndrome.
Miridesap
go.drugbank.com/drugs/DB13087InvestigationalMiridesap has been used in trials studying the prevention of HIV and treatment of AL amyloidosis.
Desmethylprodine
go.drugbank.com/drugs/DB01478ExperimentalIllicitDesmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine. … It is known to be a designer drug, synthesized in 1977, for the purpose of recreational use. Illicit manufacturing has occurred.
Empesertib
go.drugbank.com/drugs/DB19473InvestigationalEmpesertib has a monoisotopic molecular weight of 559.17 Da. … The usage of the INN stem '-sertib' in the name indicates that Empesertib is a serine/threonine kinase inhibitor.
Mevociclib
go.drugbank.com/drugs/DB21454InvestigationalMevociclib is under investigation in clinical trial NCT03134638 (A Study of SY-1365 in Adult Patients With Advanced Solid Tumors). Mevociclib has a monoisotopic molecular weight of 586.26 Da. … The usage of the INN stem '-ciclib' in the name indicates that Mevociclib is a cyclin dependant kinase inhibitor.
Risvodetinib
go.drugbank.com/drugs/DB21602InvestigationalRisvodetinib has a monoisotopic molecular weight of 574.28 Da. … The usage of the INN stem '-tinib' in the name indicates that Risvodetinib is a tyrosine kinase inhibitor.