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AMT-162
go.drugbank.com/drugs/DB17922InvestigationalAMT-162 is an adeno-associated virus serotype rh10 encoding artificial anti-SOD1 miRNA.
AVID-200
go.drugbank.com/drugs/DB18454InvestigationalAVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Synonyms: Tgf-beta 1/3 inhibitor avid200, Tgf-.beta. ligand trap comprised of tgf-.beta. receptor ectodomains fused to a human fc domain (avid-200)MDR-101
go.drugbank.com/drugs/DB18513InvestigationalMDR-101 is a CD34+ hematopoietic stem and progenitor cells with CD3+ T-cells
Tildacerfont
go.drugbank.com/drugs/DB18545InvestigationalTildacerfont is a corticotropin-releasing factor receptor-1 antagonist containing an unfused thiazole ring
Synonyms: 3-(5-chloro-2-morpholin-4-yl-thiazol-4-yl)-7-(1-ethyl-propyl)-2,5-dimethyl-pyrazolo(1,5-a)pyrimidine, Pyrazolo(1,5-a)pyrimidine, 3-(4-chloro-2-(4-morpholinyl)-5-thiazolyl)-7-(1-ethylpropyl)-2,5-dimethyl-Ergidina
go.drugbank.com/drugs/DB18565ExperimentalErgidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Synonyms: Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic RGD-4C peptide (ACDCRGDCFCG)SER-100
go.drugbank.com/drugs/DB16013InvestigationalSER-100 is under investigation in clinical trial NCT01987284 (SER100 in Isolated Systolic Hypertension).
Demcizumab
go.drugbank.com/drugs/DB12734InvestigationalDemcizumab is under investigation for the treatment of Nonsquamous Nonsmall Cell Neoplasm of Lung.
Ricolinostat
go.drugbank.com/drugs/DB12376InvestigationalRicolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
Categories: Heterocyclic Compounds, 1-RingISA101b
go.drugbank.com/drugs/DB18694InvestigationalISA101b (peltopepimut-S) is a therapeutic vaccine against the HPV-specific E6/E7 oncoproteins.
Synonyms: Peltopepimut-SIrpagratinib
go.drugbank.com/drugs/DB18732InvestigationalIrpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4.
Synonyms: 2-Propenamide, N-[(3S,4S)-3-[[6-(2,6-difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-2H-pyran-4-yl]-, N-[(3S,4S)-3-[[6-(2,6-Difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-2H-pyran-4-yl]-2-propenamide