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Displaying results 6461 - 6470 of 8517 in total
  1. Drug

    Matsupexole

    go.drugbank.com/drugs/DB21715
    Experimental

    Matsupexole has a monoisotopic molecular weight of 446.25 Da.

  2. Drug

    Balinatunfib

    go.drugbank.com/drugs/DB21728
    Investigational

    Balinatunfib has a monoisotopic molecular weight of 502.19 Da.

  3. Drug

    Rogocekib

    go.drugbank.com/drugs/DB21739
    Investigational

    Rogocekib has a monoisotopic molecular weight of 408.15 Da.

  4. Drug

    Lubiprostone

    go.drugbank.com/drugs/DB01046
    ApprovedInvestigational

    Lubiprostone is a medication used in the management of idiopathic chronic constipation. A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastroi...

  5. Drug

    Stem-cell derived exosome vesicle products

    go.drugbank.com/drugs/DB15743
    Experimental

    Mesenchymal stem cells (MSCs) exert their therapeutic effects through multiple modalities, including paracrine factors such as exosomes.

  6. Drug

    Aptazapine

    go.drugbank.com/drugs/DB09305
    Experimental

    Although Aptazapine reached clinical trials, it was never marketed. … Aptazapine (CGS-7525A) was a tetracyclic antidepressant developed in the 1980s. Aptazapine had noradrenergic and specific serotonergic activity.

  7. Drug

    Olesoxime

    go.drugbank.com/drugs/DB05185
    Investigational

    Olesoxime is a cholesterol-like small molecule that has demonstrated a remarkable neuroprotective profile in a battery of both in vitro and in vivo preclinical models. … For example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and accelerate neuroregeneration following nerve trauma.[A3282,A253233]

  8. Drug

    BMS-986020

    go.drugbank.com/drugs/DB14948
    Investigational

    BMS-986020 is under investigation in clinical trial NCT02017730 (To Evaluate The Relationship Between Plasma Drug Levels And Receptor Binding in Lung Using PET (Positron Emission Tomography) In Healthy

    Salts: BMS-986020 sodium
  9. Drug

    Bimagrumab

    go.drugbank.com/drugs/DB12584
    Investigational

    Bimagrumab has been used in trials studying the treatment and supportive care of Sarcopenia, Skeletal Muscle, Mechanical Ventilation, Sporadic Inclusion Body Myositis, and Sporadic Inclusion Body Myositis

  10. Drug

    Bencyclane

    go.drugbank.com/drugs/DB13488
    Experimental

    It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.