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Flizasertib
go.drugbank.com/drugs/DB21613InvestigationalFlizasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Flizasertib is a serine/threonine kinase inhibitor. … Flizasertib is under investigation in clinical trial NCT06602453 (A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse
Categories: Heterocyclic Compounds, 1-RingNitenpyram
go.drugbank.com/drugs/DB11438ExperimentalVet approvedIt is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly in the central nervous system of insects, causing rapid death. … Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets.
Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingSynonyms: (1E)-N-((6-chloro-3-pyridinyl)methyl)-N-ethyl-N'-methyl-2-nitro-1,1-ethenediamine, (E)-nitenpyramRacivir
go.drugbank.com/drugs/DB12753InvestigationalRacivir is a 50:50 mixture of [emtricitabine] and its positive enantiomer. Racivir has been used in trials studying the prevention of HIV Infections. … Racivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine.
Categories: Heterocyclic Compounds, 1-RingSS1(dsFv)-PE38
go.drugbank.com/drugs/DB17579InvestigationalSS1(dsFv)-PE38 is a recombinant anti-mesothelin immunotoxin. … SS1(dsFv)-PE38 is under investigation in clinical trial NCT01051934 (A Phase I Trial of SS1 (Dsfv) PE38 With Paclitaxel, Carboplatin, and Bevacizumab in Subjects With Unresectable Non-small Cell Lung Adenocarcinoma
Tralesinidase alfa
go.drugbank.com/drugs/DB17657InvestigationalTralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. … It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.[A258828]
Categories: beta-N-AcetylhexosaminidasesSynonyms: Recombinant human NAGLU-insulin-like growth factor II, Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion proteinLinopristin
go.drugbank.com/drugs/DB19296ExperimentalLinopristin is an antibiotic of the streptogramin B class. It is one part of the combination product NXL 103, along with [Virginiamycin M1].
1-Dodecanol
go.drugbank.com/drugs/DB06894Experimental1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a floral odor and is used in detergents, lubricating oils, and pharmaceuticals.
Synonyms: Dodecan-1-olATG-Fresenius S
go.drugbank.com/drugs/DB05320InvestigationalATG-Fresenius S is a concentrated anti-human T-lymphocyte immunoglobulin preparation derived from rabbits after immunization with a T-lympoblast cell line. … ATG-Fresenius S is an immunosuppressive product for the prevention and treatment of acute rejection following organ transplantation.
Synonyms: ATG-Fresenius STC-5231
go.drugbank.com/drugs/DB05333ExperimentalTC-5231 is a small molecule that has been under investigation as an oral treatment for ADHD (Attention Deficit/Hyperactivity Disorder). … TC-5231 is mecamylamine hydrochloride, the active ingredient in FDA-approved product, Inversine, but in a lower dose than Inversine.
(R)-warfarin
go.drugbank.com/drugs/DB08496ExperimentalS-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A1038] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.
Categories: Vitamin K Antagonists, Cytochrome P-450 SubstratesSynonyms: R,R-Warfarin alcohol, R-warfarin