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Displaying results 6511 - 6520 of 10000 in total
  1. Drug

    Sorbitol

    go.drugbank.com/drugs/DB01638
    ApprovedInvestigational

    It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. … A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose.

    Synonyms: G-ol, D-SorbitMixtures: Cystosol W 3% Hexitols, INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion)
  2. Drug

    4-hydroxybenzoyl-CoA

    go.drugbank.com/drugs/DB01652
    Experimental

    Synonyms: 4-hydroxybenzoyl coenzyme A, 4-hydroxybenzoyl-coenzyme ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring
  3. Drug

    Roflumilast

    go.drugbank.com/drugs/DB01656
    ApprovedInvestigational

    Roflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor. … [A251385] PDE4 is a major cyclic-3',5′-adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme [L37564] expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: DAXAS®
  4. Drug

    Methacrylyl-Coenzyme A

    go.drugbank.com/drugs/DB01675
    Experimental

    Synonyms: Methacrylyl-Coenzyme ACategories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Histamine

    go.drugbank.com/drugs/DB05381
    ApprovedInvestigational

    It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. … A depressor amine derived by enzymatic decarboxylation of histidine.

    Synonyms: 2-(4-imidazolyl)ethylamine, 4-imidazoleethylamineMixtures: Histamine DHCl 0.10 Percent and Menthol 2 Percent
  6. Drug

    Canertinib

    go.drugbank.com/drugs/DB05424
    Investigational

    Canertinib is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo.

    Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  7. Drug

    Ezatiostat

    go.drugbank.com/drugs/DB05460
    Investigational

    This medication is known to target Glutathione S-transferase P. Ezatiostat is a small molecule drug that is an analog inhibitor of glutathione S-transferase P1-1. … It might also be relevant as an adjunct therapy since a reduction in blood cell levels is also a common, toxic effect of many standard chemotherapeutic drugs.

    Synonyms: gamma-Glutamyl-S-(benzyl)-cysteinyl-R(-)-phenylglycine diethyl ester
  8. Drug

    Budiodarone

    go.drugbank.com/drugs/DB05519
    Investigational

    Budiodarone (ATI-2042) is an antiarrhythmic related to amiodarone that is currently being studied in clinical trials.

    Categories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Naronapride

    go.drugbank.com/drugs/DB05542
    Investigational

    Synonyms: (3R)-1-AZABICYCLO(2.2.2)OCT-3-YL 6-((3S,4R)-4-((4-AMINO-5-CHLORO-2- METHOXYBENZOYL)AMINO)-3-METHOXYPIPERIDIN-1-YL)HEXANOATE, 1-PIPERIDINEHEXANOIC ACID, 4-((4-AMINO-5-CHLORO-2-METHOXYBENZOYL)AMINO)-3-METHOXY-, 1-AZABICYCLO(2.2.2)OCT-3-YL ESTER, (3S,4R)-Categories: Serotonin 5-HT4 Receptor Agonists, Serotonin Receptor Agonists
  10. Drug

    Regrelor

    go.drugbank.com/drugs/DB05553
    Investigational

    Categories: Heterocyclic Compounds, 2-Ring, Purinergic P2 Receptor Antagonists