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ADX-10061
go.drugbank.com/drugs/DB05419ExperimentalADX10061 is a potent, selective antagonist of the dopamine D1 receptor. It is developed by Addex Pharmaceuticals for the treatment of nicotine dependence.
Gam-COVID-Vac
go.drugbank.com/drugs/DB15848InvestigationalPreliminary results suggested that all participants developed antibodies to the SARS-CoV-2 glycoproteins with a good safety profile in both trials. … The vaccine candidate is a heterologous COVID-19 vaccine containing two components, recombinant adenovirus type 26 (rAd26) vector and recombinant adenovirus type 5 (rAd5) vector which both carry the SARS-CoV
anti-alpha5Beta1-integrin antibody
go.drugbank.com/drugs/DB05870ExperimentalThe integrin alpha5beta1 has been shown to play a critical role during angiogenesis. anti-alpha5beta1 integrin antibody inhibits angiogenesis, including vessel formation induced by vascular endothelial
Dimethylthiambutene
go.drugbank.com/drugs/DB01444ExperimentalIllicitIt is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.
VX-702
go.drugbank.com/drugs/DB05470InvestigationalIn the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Vemtoberant
go.drugbank.com/drugs/DB21607InvestigationalVemtoberant is under investigation in clinical trial NCT05139615 (A Study to Assess the Hemodynamic Effects, Safety, Tolerability, and Pharmacokinetics of Intravenous APD418 in Adult Participants With
Surabgene lomparvovec
go.drugbank.com/drugs/DB21780InvestigationalSurabgene Lomparvovec is under investigation in clinical trial NCT07007065 (Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity
CGC-11047
go.drugbank.com/drugs/DB05722InvestigationalCGC-11047 is a polyamine analog designed to halt cell growth and induce apoptosis.
EGT-301
go.drugbank.com/drugs/DB17649ExperimentalIt consists of an adeno-associated viral vector serotype 9 (AAV9) containing the human Iduronate-2-sulfatase (I2S) transgene designed to restore I2S functional deficiency in patients with Hunter syndrome