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Albinterferon Alfa-2B
go.drugbank.com/drugs/DB05396InvestigationalRecombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. … The drug was under investigation as an alternative to pegylated IFN-α-2a for the treatment of hepatitis C.
Sitaxentan
go.drugbank.com/drugs/DB06268ApprovedWithdrawnIn 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity. … Sitaxentan was marketed under the trade name Thelin for the treatment of pulmonary arterial hypertension (PAH) by Encysive Pharmaceuticals until Pfizer purchased Encysive in February 2008.
Bevurogant
go.drugbank.com/drugs/DB21507ExperimentalBevurogant has a monoisotopic molecular weight of 532.2 Da. … The usage of the INN stem '-rogant' in the name indicates that Bevurogant is a retinoic acid receptor-related orphan receptor gamma (RORY) antagonist and inverse agonist.
Isospaglumic acid
go.drugbank.com/drugs/DB19650InvestigationalIsospaglumic acid has a monoisotopic molecular weight of 304.09 Da. … Isospaglumic acid is a small molecule drug.
Izumerogant
go.drugbank.com/drugs/DB21604ExperimentalIzumerogant has a monoisotopic molecular weight of 495.11 Da. … The usage of the INN stem '-rogant' in the name indicates that Izumerogant is a retinoic acid receptor-related orphan receptor gamma (RORY) antagonist and inverse agonist.
Glovadalen
go.drugbank.com/drugs/DB21709InvestigationalGlovadalen has a monoisotopic molecular weight of 475.14 Da. … Glovadalen is under investigation in clinical trial NCT06970301 (A Study to Assess the Safety and Tolerability, and Pharmacokinetics of UCB0022 in Healthy Caucasian, Japanese, and Chinese Participants)
Etifoxine
go.drugbank.com/drugs/DB08986ApprovedWithdrawnIt does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiazepines. It is more effective than lorazepam as an anxiolytic, and has fewer side effects. … Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing.
Telratolimod
go.drugbank.com/drugs/DB19590InvestigationalTelratolimod has a monoisotopic molecular weight of 593.47 Da. … Telratolimod is a small molecule drug. The usage of the INN stem '-tolimod' in the name indicates that Telratolimod is a toll-like receptor (TLR) agonist.
Rezivertinib
go.drugbank.com/drugs/DB21471InvestigationalRezivertinib has a monoisotopic molecular weight of 486.24 Da. … Rezivertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Rezivertinib is a epidermal growth factor receptor (EGFR) inhibitor.
Opnurasib
go.drugbank.com/drugs/DB21583InvestigationalOpnurasib has a monoisotopic molecular weight of 525.2 Da. … Opnurasib is a small molecule drug. The usage of the INN stem '-rasib' in the name indicates that Opnurasib is a Ras protein inhibitor.