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Displaying results 6531 - 6540 of 10000 in total
  1. Target

    Taste receptor type 2 member 4

    go.drugbank.com/bio_entities/BE0020472
    TargetHumans

    Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.

    Polypeptides: Taste receptor type 2 member 4
  2. Target

    Neuropeptide Y receptor type 4-2

    go.drugbank.com/bio_entities/BE0024014
    TargetHumans

    The rank order of affinity for these polypeptides and their derivatives is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13

    Polypeptides: Neuropeptide Y receptor type 4-2
  3. Drug

    Thiotepa

    go.drugbank.com/drugs/DB04572
    ApprovedInvestigational

    It is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. … N,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: N,N′,N′′-tri-1,2-ethanediyl-, Phosphorothioic triamide, N,N′,N′′-tri-1,2-ethanediyl-
  4. Target

    Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

    go.drugbank.com/bio_entities/BE0000044
    TargetHumans

    Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity).

    Polypeptides: Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylatingFunction: 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity
  5. Drug

    Granaticin B

    go.drugbank.com/drugs/DB17273
    Investigational

    Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingSynonyms: 8,11-ethanofuro(2,3-e)naphtho(2,3-c:6,7-c')dipyran-2,6,13(9h)-trione, 3,3a,5,8,11,13b-hexahydro-7,8,12-trihydroxy-5,9-dimethyl-15-(((2s,5s,6s)-tetrahydro-5-hydroxy-6-methyl-2h-pyran-2-yl)oxy)-, (3as,5s, Granaticin B
  6. Drug

    Letrozole

    go.drugbank.com/drugs/DB01006
    ApprovedInvestigational

    [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. … [A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623]

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: LETARA® 2.5 MG TABLETAS, LETROZOL® 2.5 MG TABLETAS
  7. Target

    Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase

    go.drugbank.com/bio_entities/BE0023607
    EnzymeHumans

    Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin, a step in the uric acid degradation pathway following urate oxidation (By similarity

    Polypeptides: Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylaseSynonyms: Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
  8. Drug

    Moexipril

    go.drugbank.com/drugs/DB00691
    ApprovedInvestigational

    Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension).

    Mixtures: UNIRETIC 15 MG/ 25 MG FILM KAPLI TABLET, 30 ADET, UNIRETIC 7,5 MG/ 12.5 MG FILM KAPLI TABLET, 30 ADETCategories: Heterocyclic Compounds, 2-Ring
  9. Target

    3-oxo-5-alpha-steroid 4-dehydrogenase

    go.drugbank.com/bio_entities/BE0004887
    EnzymeTargetHumans

    Catalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed … Catalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed

    Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 2, 3-oxo-5-alpha-steroid 4-dehydrogenase 1Synonyms: 3-oxo-5-alpha-steroid 4-dehydrogenase 3, S5AR 2
  10. Drug

    Miglitol

    go.drugbank.com/drugs/DB00491
    Approved

    It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) into … Miglitol should be taken at the start of a meal for maximal effect and the effect will depend on the amount of poly and oligosaccharides in the diet.

    Categories: Heterocyclic Compounds, 1-RingProducts: MIOL 25 MG TABLET ,100 TABLET, MIGLITEC 25 MG TABLET, 100 ADET