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AVI-4065
go.drugbank.com/drugs/DB05620InvestigationalAVI-4065, a phosphorodiamidate Morpholino oligomer (PMO), is an investigational antisense HCV drug. It was developed by Sarepta Therapeutics, Inc. After phase II trials it was cancelled due to lack of potency.
ISIS 14803
go.drugbank.com/drugs/DB05803InvestigationalISIS 14803 is a 20-unit antisense phosphorothioate oligodeoxynucleotide that binds to hepatitis C virus (HCV) RNA at the translation initiation region of the internal ribosome entry site (IRES) and inhibits protein expression in cell cul...
AV-412
go.drugbank.com/drugs/DB06021InvestigationalCategories: Receptor, ErbB-2, antagonists & inhibitors, Erb-b2 Receptor Tyrosine Kinases, antagonists & inhibitorsApatorsen
go.drugbank.com/drugs/DB06094InvestigationalApatorsen is a second generation antisense drug which in preclinical experiments, inhibits production of Heat Shock Protein 27 (Hsp27) a cell survival protein found at elevated levels in many human cancers including prostate, lung, breas...
Naxifylline
go.drugbank.com/drugs/DB06471ExperimentalCategories: Adenosine A1 Receptor Antagonists, Purinergic P1 Receptor AntagonistsMLN2222
go.drugbank.com/drugs/DB06503ExperimentalMLN2222 is a novel, proprietary recombinant protein that blocks both the C3 and C5 convertases, which are essential components of the complement activation pathway.
AM365
go.drugbank.com/drugs/DB06564ExperimentalDetiviciclovir (AM365) is an antiviral nucleoside analogue.