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Andrographolide
go.drugbank.com/drugs/DB05767InvestigationalThe herb has an extensive history of use in TCM for the treatment of upper respiratory tract infections and other inflammatory and infectious diseases.
Coltuximab ravtansine
go.drugbank.com/drugs/DB06342InvestigationalColtuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic leukemia (ALL).
Synonyms: Anti-CD19 humanized monoclonal antibody conjugated to DM4Chlorfenson
go.drugbank.com/drugs/DB05377ExperimentalChlorfenson is developed by Moberg Derma for the treatment of onychomycosis (nail fungus) as the primary indication.
T-5224
go.drugbank.com/drugs/DB05998ExperimentalT-5224 is an investigational drug developed to treat Sepsis-induced Acute Kidney Injury. It's mechanism of action is to inhibit c-Fos/activator protein-1.
Iroxanadine
go.drugbank.com/drugs/DB05444ExperimentalBRX-235 also causes translocation of calcium-dependent protein kinase C isoform to membranes.
Tertomotide
go.drugbank.com/drugs/DB12747InvestigationalIt is a peptide vaccine that activates the immune system so that it recognizes and kills cancer cells. It is being developed by Pharmexa A/S. … Tertomotide is under investigation in clinical trial NCT01223209 (A Study, Combination, Immunologic Study of LTX-315 as adjunct to tertomotide in Patients Following Curative Surgery for Carcinoma).
Platelet Lysate
go.drugbank.com/drugs/DB15869InvestigationalPlatelet lysate is an acellular compound composed of platelet proteins while also being void of cellular debris, thus making the lysate rich with growth factors. … [A220188] It is extracted through lysis of the plasma membrane of platelets. Because white cell antigens are low in prepared lysate, there is a minimized likelihood of immune responses.
Interleukin-7
go.drugbank.com/drugs/DB11997InvestigationalInterleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer.
ABT-510
go.drugbank.com/drugs/DB05434InvestigationalIt is developed by Abbott Laboratories for the treatment of Solid Tumors, Lymphoma and Melanoma.
Linsitinib
go.drugbank.com/drugs/DB06075InvestigationalAn orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. … IGF-1R inhibitor OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis.