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Encenicline
go.drugbank.com/drugs/DB11726InvestigationalEncenicline has been investigated for the treatment of Cognition, Schizophrenia, Alzheimer's Disease, Cardiac Repolarization, and Central Nervous System Diseases.
Categories: Heterocyclic Compounds, 1-RingICA-105665
go.drugbank.com/drugs/DB06089InvestigationalICA-105665 is a novel small molecule compound for the treatment of epilepsy. … It is a novel opener of the KCNQ ion channel which in preclinical studies has demonstrated a broad spectrum of activity in models of epilepsy.
Razuprotafib
go.drugbank.com/drugs/DB16353InvestigationalRazuprotafib, also known as AKB-9778, is a small-molecule inhibitor restoring Tie2 activation by inhibiting VE-PTP. … [L27171,L27176] In investigations against diabetes and COVID-19, razuprotafib is self-administered by patients through subcutaneous injection.
Emricasan
go.drugbank.com/drugs/DB05408InvestigationalEmricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA. … It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis.
Cianopramine
go.drugbank.com/drugs/DB19470ExperimentalCianopramine is a small molecule drug. The usage of the INN stem '-pramine' in the name indicates that Cianopramine is a substance of the imipramine group. … Cianopramine has a monoisotopic molecular weight of 305.19 Da.
Categories: Heterocyclic Compounds, 3-RingAzipramine
go.drugbank.com/drugs/DB19636ExperimentalAzipramine is a small molecule drug. The usage of the INN stem '-pramine' in the name indicates that Azipramine is a substance of the imipramine group. … Azipramine has a monoisotopic molecular weight of 366.21 Da.
Depramine
go.drugbank.com/drugs/DB20198ExperimentalDepramine is a small molecule drug. The usage of the INN stem '-pramine' in the name indicates that Depramine is a substance of the imipramine group. … Depramine has a monoisotopic molecular weight of 278.18 Da.
Categories: Heterocyclic Compounds, 3-RingSynonyms: Imipramine hydrochloride impurity bKetipramine
go.drugbank.com/drugs/DB21245ExperimentalKetipramine is a small molecule drug. The usage of the INN stem '-pramine' in the name indicates that Ketipramine is a substance of the imipramine group. … Ketipramine has a monoisotopic molecular weight of 294.17 Da.
Categories: Heterocyclic Compounds, 3-RingCMLVAX100
go.drugbank.com/drugs/DB05164ExperimentalCMLVAX100 is a vaccine targeting the BCR-ABL-derived p210 fusion protein which reduces residual disease in some patients with chronic myeloid leukemia. … It is developed by Breakthrough Therapeutics and has completed phase I of its clinical trial.
OSI-461
go.drugbank.com/drugs/DB05415InvestigationalOSI-461 is a second-generation molecule belonging to a new class of drugs termed selective apoptotic anti-neoplastic drugs (SAANDs).