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L523S
go.drugbank.com/drugs/DB06498Investigationaland when delivered following incorporation into an E1B-deleted adenovirus (Ad/L523S)." … According to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S)
Peginterferon lambda-1a
go.drugbank.com/drugs/DB14767InvestigationalPeginterferon lambda-1a is under investigation in clinical trial NCT01754974 (Safety and Efficacy Study of Peginterferon Lambda-1a vs.
Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsSetiptiline
go.drugbank.com/drugs/DB09304ExperimentalSetiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).
Tienilic acid
go.drugbank.com/drugs/DB04831ApprovedWithdrawnIt was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Dimetacrine
go.drugbank.com/drugs/DB08996ApprovedWithdrawnIt is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil.
Epirizole
go.drugbank.com/drugs/DB08991ExperimentalEpirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.
Lirilumab
go.drugbank.com/drugs/DB11754InvestigationalLirilumab has been used in trials studying the treatment of Leukemia, CANCER,NOS, Multiple Myeloma, Lymphocytic Leukemia, and Acute Myeloid Leukemia, among others.
Categories: Amino Acids, Peptides, and ProteinsOrticumab
go.drugbank.com/drugs/DB16653InvestigationalOrticumab is under investigation in clinical trial NCT04776629 (A Proof-of-activity Study With Orticumab in Subjects With Psoriasis and Cardiometabolic Risk Factors).
Categories: Amino Acids, Peptides, and ProteinsN-omega-nitro-L-arginine methyl ester
go.drugbank.com/drugs/DB12750InvestigationalL-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury.
Categories: Amino Acids, Peptides, and ProteinsMalonyl-CoA
go.drugbank.com/drugs/DB04524ExperimentalA coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.
Categories: Enzymes and Coenzymes, Nucleic Acids, Nucleotides, and Nucleosides