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Hetrombopag
go.drugbank.com/drugs/DB16184InvestigationalHetrombopag is under investigation in clinical trial NCT03976882 (Hetrombopag for the Treatment of Chemotherapy-induced Thrombocytopenia in Subjects With Malignancy.).
Categories: Heterocyclic Compounds, 1-RingHQP1351
go.drugbank.com/drugs/DB16185InvestigationalHQP1351 is under investigation in clinical trial NCT03883100 (A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Accelerated Phase With T315I Mutation).
Categories: Heterocyclic Compounds, 1-RingLocnartecan
go.drugbank.com/drugs/DB16186InvestigationalPEN-866 is under investigation in clinical trial NCT03221400 (PEN-866 in Patients With Advanced Solid Malignancies).
Synonyms: Hsp90-targeted sn-38 conjugate pen-866Tovinontrine
go.drugbank.com/drugs/DB16193InvestigationalTovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor. … Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With Sickle Cell Disease).
Synonyms: 6-((3S,4S)-4-METHYL-1-(2-PYRIMIDINYLMETHYL)-3-PYRROLIDINYL)-3-(TETRAHYDRO-2H-PYRAN-4-YL)IMIDAZO(1,5-A)PYRAZIN-8(7H)-ONE, 6-[(3S,4S-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imadazo[1,5-a]pyrazin-8-oneISIS 104838
go.drugbank.com/drugs/DB16201InvestigationalISIS 104838 is under investigation in clinical trial NCT00048321 (ISIS 104838, an Inhibitor of Tumor Necrosis Factor, for Active Rheumatoid Arthritis).
Itolizumab
go.drugbank.com/drugs/DB16207InvestigationalItolizumab is under investigation in clinical trial NCT04605926 (A Study to Evaluate the Efficacy and Safety of Itolizumab in Subjects Hospitalized With COVID-19).
KAI-1678
go.drugbank.com/drugs/DB16211InvestigationalKAI-1678 is under investigation in clinical trial NCT01106716 (Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic Neuralgia).
Categories: Protein Kinase C-epsilon, antagonists & inhibitorsLadostigil
go.drugbank.com/drugs/DB16213InvestigationalLadostigil is under investigation in clinical trial NCT01429623 (A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment).
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesLandipirdine
go.drugbank.com/drugs/DB16214InvestigationalLandipirdine is under investigation in clinical trial NCT02258152 (SYN120 Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)).
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsLapaquistat
go.drugbank.com/drugs/DB16215InvestigationalLapaquistat is under investigation in clinical trial NCT00256178 (Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.).
Categories: Heterocyclic Compounds, 1-Ring