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Benzoylecgonine
go.drugbank.com/drugs/DB01515ExperimentalIllicitIt is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver.
Synonyms: O-benzoylecgonine, O-benzoyl-(-)-ecgonineAGT-182
go.drugbank.com/drugs/DB17630InvestigationalAGT-182 is an investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and a human insulin receptor monoclonal antibody.
TAK-611
go.drugbank.com/drugs/DB17644InvestigationalFirst developed by Takeda, it is being investigated for the treatment of metachromatic leukodystrophy.
Azelnidipine
go.drugbank.com/drugs/DB09230InvestigationalIt is marketed by Daiichi-Sankyo pharmaceuticals, Inc. in Japan.
REC-994
go.drugbank.com/drugs/DB15616InvestigationalREC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous malformation (CCM).
Autologous Hematopoietic Peripheral Blood Stem Cells
go.drugbank.com/drugs/DB17067InvestigationalAutologous hematopoietic peripheral blood stem cells were tested in a clinical trial (NCT00424489) by Northwestern University for the treatment of refractory myasthenia gravis.
Adenosine 5'-phosphosulfate
go.drugbank.com/drugs/DB03708InvestigationalThe initial compound formed by the action of ATP sulfurylase on sulfate ions after sulfate uptake. Synonyms: adenosine sulfatophosphate; APS.
ENTR-601-44
go.drugbank.com/drugs/DB17836InvestigationalDeveloped by Entrada Therapeutics, it was investigated for the treatment of Duchenne muscular dystrophy.[L46641]
PAS-004
go.drugbank.com/drugs/DB18611InvestigationalPAS-004 is an allosteric MEK 1/2 inhibitor being developed by Pasithea Therapeutics. It is being investigated for the treatment of neurofibromatosis 1 and Noonan syndrome.
Eperisone
go.drugbank.com/drugs/DB08992InvestigationalIt is not approved for use in the United States, but is available in other countries like India, South Korea, and Bangladesh.