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DB01515ExperimentalIllicitSmall molecule
Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after... It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for the relief of muscle pain that is not FDA approved or on the market in the United States.
- Formula / weight
- C16H19NO4 · 289.3264 g/mol (avg)
- Also known as
- Ecgonine benzoate · O-benzoylecgonine
- Code names
- DEA No. 9180
Resolves to
Clinical / RWD
Structure
InChIKey
GVGYEFKIHJTNQZ-RFQIPJPRSA-NSMILES[H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)C1=CC=CC=C1)C(O)=O)N2CWhat you can answer from here — as of September 12, 2026
Which companies are running trials of Benzoylecgonine, in which indications and phases, and which of those programs are still active?