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Flizasertib
go.drugbank.com/drugs/DB21613InvestigationalFlizasertib is under investigation in clinical trial NCT06602453 (A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse
Eperisone
go.drugbank.com/drugs/DB08992InvestigationalIt is not approved for use in the United States, but is available in other countries like India, South Korea, and Bangladesh.
SAR-439459
go.drugbank.com/drugs/DB17864Investigational[A259862] Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis Imperfecta.
Utidelone
go.drugbank.com/drugs/DB17575InvestigationalUtidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue produced by genetic engineering.[A257544,A257549] It is under investigation in clinical trials for various cancers.
RLYB212
go.drugbank.com/drugs/DB17727InvestigationalIt is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.
Dipropyl-4-hydroxytryptamine
go.drugbank.com/drugs/DB13990ExperimentalDipropyl-4-hydroxytryptamine was first synthesized by Alexander Shulgin. This agent and its properties haven't been fully elucidated.
Synonyms: 4-HO-DPT, 4-Hydroxy-N,N-dipropyltryptamineEritoran
go.drugbank.com/drugs/DB04933InvestigationalIt is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Ro 24-7429
go.drugbank.com/drugs/DB16062InvestigationalRo 24-7429 is under investigation in clinical trial NCT00002314 (A Study of Ro 24-7429 in Patients With Hiv-related Kaposi's Sarcoma).
Triazavirin
go.drugbank.com/drugs/DB15622Investigational[L12087] Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating Triazavirin as an option to combat SARS-CoV-2, the coronavirus responsible for COVID-19.[A191625]
MRK-003
go.drugbank.com/drugs/DB17015ExperimentalMRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682]