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Perospirone
go.drugbank.com/drugs/DB08922InvestigationalIt also displays affinity towards 5HT1A receptors as a partial agonist. … It is also shown to be less associated with extrapyramidal symptoms as a side effect compared to [DB00502].
Amfecloral
go.drugbank.com/drugs/DB08924ExperimentalAmfecloral is a stimulant drug of the phenethylamine and amphetamine chemical classes. … It acts as a prodrug which splits to form amphetamine and chloral hydrate, similarly to clobenzorex and related compounds, except that the N-substituent, in this case, yields a compound that is active
Adrafinil
go.drugbank.com/drugs/DB08925ApprovedWithdrawnAdrafinil is a mild central nervous system stimulating drug typically employed to relieve excessive sleepiness and inattention in geriatric patients.
Arsthinol
go.drugbank.com/drugs/DB08928ExperimentalConsidered well tolerated when compared to other related trivalent organoarsenicals, arsthinol has even undergone recent studies as a potential anticancer agent.
Riociguat
go.drugbank.com/drugs/DB08931ApprovedInvestigationalRiociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for
Macitentan
go.drugbank.com/drugs/DB08932ApprovedInvestigationalMacitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013. … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October 2021 for the treatment of PAH.[L39105] It was subsequently approved by the FDA in March 2024.
Categories: Endothelin A Receptor AntagonistsLetosteine
go.drugbank.com/drugs/DB08939ExperimentalLetosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.
Kebuzone
go.drugbank.com/drugs/DB08940InvestigationalKebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.
Indoprofen
go.drugbank.com/drugs/DB08951ApprovedWithdrawnA drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
Ibuproxam
go.drugbank.com/drugs/DB08955ApprovedWithdrawnIbuproxam is a non steroidal anti-inflammatory drug (NSAID).